Drug Delivery Nanosystems: From Bioinspiration and Biomimetics to Clinical Applications

Summary

Nanotechnology seeks to exploit distinct technological advances controlling the structure of nanoscale biomaterials at a nanodimensional scale approaching individual molecules and their aggregates or supramolecular structures. The term "nanomedicine" is used to describe those technologies under the umbrella of nanotechnology that have therapeutic applications in human health. This book presents recent trends and research achievements in the field of pharmaceutical nanotechnology and advanced drug delivery nanosystems, especially for theranostic purposes. The applications of drug delivery nanosystems considered carriers of active pharmaceutical ingredients (APIs) (e.g., proteins, peptides, and nucleic acids) are analyzed on the basis of technology, preparation protocols, and biomedical applications. The book also extensively reports on the principles, design protocols, and applications of nanosystems in drug delivery, imaging, and targeting of active molecules of pharmaceutical interest.

Nanocrystals in Medical Application. 

Cyclodextrin-based Nanosystems. 

Hydrogels.  

Ocular Drug Delivery Dendrimers. 

Carbon Nanotubes. 

Metal Nanoclusters for Bio-sensing Applications. 

Computational Techniques for the Design of Self-assembled Dendrimers. 

Spherical Nucleic Acids. 

Radiolabeled Nanoparticles as Diagnostic and Therapeutic Agents of Cancer. 

In Vivo Imaging; Nanotoxicity and Health Risks.