Surface Design: Applications in Bioscience and Nanotechnology

This carefully selected balance of tutorial–like review chapters and advanced research covers hot topics in the field of biointerfaces, biosensing, nanoparticles at interfaces, and functionalized quantum dots. It also includes chapters arising from non–published work with topics such as surface design and its applications, as well as new developments in analytical tools for materials science and life science.
Based on the very close and complementary collaboration of three distinguished leading research groups, this book highlights recent advances in the field ranging from synthesis and fabrication of organic and polymeric materials, surface and interface science to advanced analytical methods. It thus addresses new concepts in micro– and nanofabrication, bio–nanotechnology, biosensors and the necessary compositional and structural analysis. Particular attention is paid throughout to complex hierarchical interface architectures and possible applications of the chemical and physical methodologies discussed, covering bio–diagnostics, novel biosensors and adhesion science.
With its unique combination of expertise from chemistry, physics, biology, surface science and engineering, this is a valuable companion for students, practitioners and established experts.

Spis treści:
Foreword.
List of Contributors.
1 Tutorial Reviews.
1.1 Coupling Chemistries for the Modification and Functionalization of Surfaces to Create Advanced Biointerfaces (Holger Schönherr).
1.2 Tutorial Review: Surface Plasmon Resonance–Based Biosensors (Jakub Dostálek, Chun Jen Huang, and Wolfgang Knoll).
1.3 Tutorial Review: Surface Modification and Adhesion (Renate Förch).
1.4 Tutorial Review: Modern Biological Sensors (A. Tobias A. Jenkins).
2 Functional Thin Film Architecture and Platforms Based on Polymers.
2.1 Controlled Block–Copolymer Thin&# 8211;Film Architectures (Monique Roerdink, Mark A. Hempenius, Ulrich Gunst, Heinrich F. Arlinghaus, and G. Julius Vancso).
2.2 Stimuli–Responsive Polymer Brushes (Edmondo Benetti, Melba Navarro, Szczepan Zapotoczny, and G. Julius Vancso).
2.3 Cyanate Ester Resins as Thermally Stable Adhesives for PEEK (Basit Yameen, Matthias Tamm, Nicolas Vogel, Arthur Echler, Renate Förch, Ulrich Jonas, and Wolfgang Knoll).
2.4 Structured and Functionalized Polymer Thin–Film Architectures (Holger Schçnherr, Chuan Liang Feng, Anika Embrechts, and G. Julius Vancso).
3 Biointerfaces, Biosensing, and Molecular Interactions.
3.1 Surface Chemistry in Forensic–Toxicological Analysis (Martin Jübner, Andreas Scholten, and Katja Bender).
3.2 Modification of Surfaces by Photosensitive Silanes (Xiaosong Li, Swapna Pradhan–Kadam, Marta Álvarez, and Ulrich Jonas).
3.3 Solid–Supported Bilayer Lipid Membranes (Ingo Köper and Inga Vockenroth).
3.4 Interaction of Structured and Functionalized Polymers with Cancer Cells (Anika Embrechts, Chuan Liang Feng, Ilona Bredebusch, Christina E. Rommel, Jürgen Schnekenburger, G. Julius Vancso, and Holger Schçnherr).
3.5 Fabrication and Application of Surface–Tethered Vesicles (Thomas Lloyd Williams and A. Tobias A. Jenkins).
3.6 Plasma–Polymerized Allylamine Thin Films for DNA Sensing (Li–Qiang Chu, Wolfgang Knoll, and Renate Förch).
4 Nanoparticles and Nanocontainers.
4.1 Defined Colloidal 3D Architectures (Nina V. Dziomkina, Mark A. Hempenius, and G. Julius Vancso).
4.2 Nanoparticles at the Interface: The Electrochemical and Optical Properties of Nanoparticles Assembled into 2D and 3D Structures at Planar Electrode Surfaces (Petra J. Cameron).
4.3 Surface Engineering of Quantum Dots with Designer Ligands (Nikodem Tomczak, Dominik Janczewski, Oya Tagit, Ming–Yong Han, and G. Julius Vancso).
4.4 Stimuli–Responsive Capsules (Yujie Ma, Mark A. Hempenius, E. Stefan Kooij, Wen–Fei Dong, Helmuth Möhwald, and G. Julius Vancso).
4.5 Nanoporous Thin Films as Highly Versatile and Sensitive Waveguide Biosensors (K.H. Aaron Lau, Petra Cameron, Hatice Duran, Ahmed I. Abou–Kandil, and Wolfgang Knoll).
5 Surface and Interface Analysis.
5.1 Stretching and Rupturing Single Covalent and Associating Macromolecules by AFM–Based Single–Molecule Force Spectroscopy (Marina I. Giannotti, Weiqing Shi, Shan Zou, Holger Schönherr, and G. Julius Vancso).
5.2 Quantitative Lateral Force Microscopy (Holger Schönherr, Ewa Tocha, Jing Song, and G. Julius Vancso).
5.3 Long–Range Surface Plasmon Enhanced Fluorescence Spectroscopy as a Platform for Biosensors (Amal Kasry, Jakub Dostálek, and Wolfgang Knoll).
Appendices: Surface Analytical Tools.
Appendix A Material Structure and Surface Analysis.
Appendix B Atomic Force Microscopy.
Appendix C Contact Angle Goniometry.
Appendix D Ellipsometry.
Appendix E Fourier Transform Infrared Spectroscopy.
Appendix F Impedance Spectroscopy.
Appendix G Scanning Electron Microscopy.
Appendix H Surface Plasmon Resonance 485.
Appendix I Optical Waveguide Spectroscopy (OWS) – lm–Thick Films.
Appendix J Waveguide Mode Spectroscopy (WaMs) – nm–Thick Films.
Appendix K X–ray Photoelectron Spectroscopy (XPS).
Index.

Nota biograficzna:
Renate Forch studied Chemistry at the University of London, King′s College and Queen Mary. After finishing her Ph.D. she went to the University of Western Ontario, Canada, where she built up a research group focussing on plasma surface modification of polymer films. Since February 1996 she has been holding a post at the Max Planck Ins titute for Polymer Research working on pulsed plasma polymerisation of thin organic films with the aim to develop functional coatings to improve surface properties of materials such as biocompatibility and tribological properties.
Holger Schonherr studied chemistry and polymer chemistry and physics in Mainz, Germany, and Toronto, Canada. After a post–doctoral position at Stanford, he became professor at the University of Twente, Netherlands. In 2008, he accepted a post as a full professor for Physical Chemistry at the University of Siegen, Germany. Professor Schonherr′s major research interests are the chemistry and physics of surfaces and interfaces, functional platforms for biointerfacing, self–organized and macromolecular systems in confinement as well as scanning force microscopy. He is the author of more than 100 peer–reviewed papers.
A. Toby A. Jenkins received his Ph.D. degree from the University of Newcastle upon Tyne, Great Britain. After a post–doc position at the University of Leeds, he was awarded an Alexander–von–Humboldt fellowship in 1999, allowing him to work at the Max–Planck Institute for Polymer Research in Mainz, Germany, where he studied the interaction of lipid vesicles with micropatterned surfaces and polymer supports. In September 2000 he became a lecturer in the department of Chemistry at the University of Bath, Great Britain.

Okładka tylna:
This carefully selected balance of tutorial–like review chapters and advanced research covers hot topics in the field of biointerfaces, biosensing, nanoparticles at interfaces, and functionalized quantum dots. It also includes chapters arising from non–published work with topics such as surface design and its applications, as well as new developments in analytical tools for materials science and life science.
Based on the very close and complementary collaboration of three distinguished leadin g research groups, this book highlights recent advances in the field ranging from synthesis and fabrication of organic and polymeric materials, surface and interface science to advanced analytical methods. It thus addresses new concepts in micro– and nanofabrication, bio–nanotechnology, biosensors and the necessary compositional and structural analysis. Particular attention is paid throughout to complex hierarchical interface architectures and possible applications of the chemical and physical methodologies discussed, covering bio–diagnostics, novel biosensors and adhesion science.
With its unique combination of expertise from chemistry, physics, biology, surface science and engineering, this is a valuable companion for students, practitioners and established experts.