Applied Bioengineering: Innovations and Future Directions

A comprehensive overview of the topic, highlighting ongoing research trends and future directions.
Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources.
With its cutting–edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, biotechnological institutes, and environmental chemists.

Advanced Biotechnology
Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley–VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.

1. Introduction

PART I –
ENZYME TECHNOLOGY
2. Enzyme Technology: History and Current Trends
3. Molecular Engineering of Enzymes
4. Biocatalytic Process Development
5. Development of Enzymatic Reactions in Miniaturized Reactors

PART II –
MICROBIAL PROCESS ENGINEERING
6. Monitoring of Fermentation Processes
7. Omics–Integrated Approach for Metabolic State Analysis of Microbial Processes
8. Process Control and PAT Management of Microbial Cultivation

PART III –
PLANT CELL CULTURE ENGINEERING
9. Contained Molecular Farming Using Plant Cell and Tissue Cultures
10. Bioprocess Engineering of Plant Cell Suspension Cultures
11. The Role of Bacteria in Phytoremediation

PART IV –
ANIMAL CELL CULTURES
12. Cell Line Development for Biomanufacturing Processes
13. Medium Design, Culture Management and the PAT Initiative
14. Advanced Bioprocess Engineering: Fed–Batch and Perfusion Processes

PART V –
ENVIRONMENTAL BIOENGINEERING
15. Treatment of Industrial and Municipal Wastewater: An Overview about Basic and Advanced Concepts
16. Treatment of Solid Waste
17. Energy Recovery from Organic Waste
18. Microbial Removal and Recovery of Metals from Wastewater
19. Sustainable Use of Phosphorus Through Bio–based Recycling


Toshiomi Yoshida is Professor Emeritus of Osaka University (Japan). He received his doctorate degree at the same university in 1968, after studying fermentation technology. From 1972 to 1973, he visited the University of Pennsylvania (USA) for a research stay. In the further course of his career, he became Associate Professor at Osaka University in 1978, Full Professor in 1988 and held several positions within the university until his retirement in 2003. From 1995 to 1999, he was Director of the International Center for Biotechnology. After his retirement, Toshiomi Yoshida was appointed as Director of the Bangkok Liaison Office of the Japan Society for the Promotion of Science, a position he hold until 2007. From 2007 to 2012, he was Director General of the Research Institute of Environmental, Agriculture and Fisheries of the Osaka Prefectural Government. In between 2009 and 2013, Toshiomi Yoshida served as the first President of the Asian Federation of Biotechnology.