Sustainable Flow Chemistry: Methods and Applications

This ready reference not only presents the hot and emerging topic of modern flow chemistry, it is also unique in illustrating the important connection to sustainable chemistry.
Focusing on more sustainable methods and applications, the text extensively covers every important field from reaction time optimization to waste minimization, and from safety improvements to microwave applications. In addition, green metrics are presented as a key aspect of the book, helping readers to evaluate the efficiency of flow technologies and their impact on the overall efficiency of a chemical process.
An invaluable handbook for every chemist working in the laboratory, whether in academia or industry.

Reaction time optimization
Minimization of time for screening
Waste minimization
Energy consumption optimization
Safety improvements
Process intensification and scale–up
Supercritical fluids
New process windows
Microwave in flow


Luigi Vaccaro is a Professor of Organic Chemistry (habilitated in 2013 as full Professor 03/C1) at the Università di Perugia, Italy, a Guest Professor (Bijzonder Gastdocent) at the University of KU Leuven, Belgium, and he has been appointed as Associate Editor of RSC Advances and Beilstein Journal of Organic Chemistry. Prof. Vaccaro is leading Green S.O.C. group and is dedicating his research and teaching activity to the development of sustainable tools for minimizing waste and accessing cleaner products. He is currently focusing on the identification and use of novel biomass–derived solvents and on the design and synthesis of novel polymeric matrices for the preparation of heterogeneous catalytic systems adequate for being used in flow and safer reaction. Recent applications are directed to the definition of green protocols for cross–coupling and C H activation processes for the clean synthesis of organic semiconductors and target materials. Luigi Vaccaro is Author of ca. 130 scientific publications and received the Europa Medal from Society of Chemical Industry – London (2001), the ADP Award from Merck′s Chemistry Council for "Creative work in organic chemistry" (2006 and 2007), the G. Ciamician Medal of the Società Chimica Italiana (2007) and the Vigevani Visiting Professorship (2014). He is also member of the FWO WT&4 expert panel and OECD–EPA commission on substitution of toxic substances.