Handbook of Metathesis: 3 Volume Set

The tremendous success of the metathesis reaction over the last decade is reflected in its huge impact on organic, polymer, and organometallic chemistry. It is highly reliable and produces few by–products, making it environmental friendly. Beside its academic use, many industrial applications in petrochemistry, agro– and pharmachemistry, as well as in the field of fine chemicals and material science have been developed and further underscore the importance of this fascinating reaction.
This second edition of the "bible" in this field has been completely updated and now features more than 80% new content, with the focus on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality.
Edited by a Nobel laureate in the field, and with a list of contributors that reads like a "Who′s–Who" of metathesis, this is an indispensable one–stop reference for organic, polymer and industrial chemists, as well as chemists working with organometallics.

VOLUME 1 –
CATALYST DEVELOPMENT AND MECHANISM
Preface
Development of Selective Ruthenium–Based Catalysts
Development of Selective Mo– and W–Based Catalysts
Alkane Metathesis
Diastereocontrol in Olefin Metathesis
CAAC Catalysts in Olefin Metathesis
Enantioselective Olefin Metathesis Catalysts
Supported Catalysts and Catalysts in Heterogeneous Media
Computational Investigations of Olefin Metathesis
Intermediates in Olefin Metathesis

VOLUME 2 –
APPLICATIONS IN ORGANIC SYNTHESIS
Olefin Metathesis in Organic Synthesis (introductory chapter)
General Ring–Closing Metathesis
Olefin Cross Metathesis
Tandem Metathesis Reactions
Ene–Yne Metathesis
Alkyne Metathesis
Metathesis of Silicon–Containing Olefins
Olefin Metathesis Strategies in the Synthesis of Biologically Relevant Molecules
Metathesis in Peptide Systems
Metathesis in Carbohydrates
Olefin Metathesis for Chemical Biology
Industrial Applications of Metathesis–at–Scale in the Pharmaceutical Industry
Metathesis Strategies for Diversity–Oriented Synthesis/Drug Discovery
Industrial Applications of Metathesis in the Production of Feedstock and Renewable Fine Chemicals
Heterocycles via Metathesis

VOLUME 3 –
POLYMER SYNTHESIS
Ring Opening Metathesis Polymerization (ROMP)
Synthesis of Homo– and Co–polymers
Latent ruthenium initiators for ROMP
ROMP of oxygen containing norbornene derivatives
Synthesis of biodegradable graft copolymers
Biological Applications of ROMP polymers
Self–healing materials
Synthesis of thermally degradable thermosets
Supramolecular polymers
ADMET Polymerization
Polymers from bio materials using metathesis
Telechelic polymers
Polydicyclopentadiene and applications
Modification of polyolefins



Robert H. Grubbs received his Ph.D. from Columbia University for work with Ron Breslow. After a postdoctoral year with Jim Collman at Stanford University, he joined the faculty at Michigan State University. In 1978, he moved to the California Institute of Technology, where he is now the Victor and Elizabeth Atkins Professor of Chemistry. Among many other awards he received the Nobel Prize in 2005 for his research on the metathesis reaction. His research interests include polymer chemistry, organometallic catalysis, and development of new synthetic organic methodology.

Anna Wenzel received her PhD at Harvard University under the guidance of Prof. E. N. Jacobsen. From 2003 to 2006 she joined the group of Prof. R. H. Grubbs as NIH Postdoctoral Scholar. Since 2006 she is Assistant Professor at the W. M. Keck Science Department in Claremont, California. Her research topics are asymmetric catalysis, organometallic chemistry, and organic synthesis.

Daniel O´Leary received his PhD in the group of Prof. Anet. After a postdoctoral stay with Prof. Kishi (Harvard University), he became Assistant Professor at Pomona College where he became Full Professor in 2007. Since 2008 he is John S. Osterweis Professor of Chemistry & Biochemistry at Bowdoin College. His research interests are organic chemistry and nuclear magnetic resonance.

Ezat Khosravi is reader in the Department of Chemisstry at the University of Durham, UK. His research interests are in the field of synthetic polymer chemistry and involve synthesis, characterisation and evaluation of well–defined novel polymeric materials.