Monolithic Silicas in Separation Science: Concepts, Syntheses, Characterization, Modeling and Applications

Edited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must–have information hitherto only scattered among journals.
Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.


Spis treści:
Introduction
PREPARATION
Synthetic Concept, Preparation of Silica Monoliths
Preparation and Properties of Various Monolithic Silica Stationary Phases for RP, HILIC; and Ion Exchange Mode Based on Polymer Coated Materials
CHARACTERIZATION AND MODELIND
Physico–chemical and Chromatographic Characterization
Microscopic Characterization
Modeling and Simulation
Comparision of Column Performance of Particle Packed and Monolithic Columns for HPLC
APPLICATIONS
Basic Aspects to Control Selectivity of RPLC on Monolithic Silica Materials
Applications of Silica Monoliths for the Separation of Low Molecular Weight Compounds and in Pharmacokinetics
Performance for Basic Compounds. Silanol Activity
LC–MS of Small MW Compounds
Analysis of Food and Beverages
Quality Control of Drugs
Monolithic Stationary Phases for Fast Ion Chromatography
Monolithic Columns for Chiral Separation
Capillary Electrochromatography
Silica Capillaries for on–line and off–line MS Analysis
Silica Monoliths for Preparative Analysis
Monolithic Silica Columns in Mulitdimensional LC–MS for Proteomics and Peptidomics
SPE and SPME Applications
REFERENCES AND FURTHER READING


Nota biograficzna:
Nobuo Tanaka studied chemistry at Kyoto University, Japan. After his postdocs in the US at the Universities of Pennsylvania, Washington and Northeastern University, he came back to Kyoto, where he is Professor at the Institute of Technology. His research interests include development of chro matographic columns and stationary phases, separation of isotopes, isomers and environmental contaminants on solid surfaces. He is editor of Wileys Journal of Separation Science as well as others. He received several awards as the Environmental Award (1994), Award from the Society for Chromatographic Sciences (1998), the Jubilee Silver Medal of the UK Chromatographic Society (2002) and the Japan Society for Analytical Chemistry Award (2004).
Klaus K. Unger started his research career at the Technical University of Darmstadt, Germany, before he moved to the University of Mainz, Germany. He is one of the pioneers in the development of silica based materials for HPLC. He published many scientific papers as well as successful books.
Egidijus Machtejevas is postdoc in the research group of Klaus K. Unger and co–authored already many research papers.