Surface Enhanced Raman Spectroscopy: Analytical, Biophysical and Life Science Applications

Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface–enhanced Raman scattering (SERS) for solving real world problems.
From the contents:Theory and practice of SERSAnalytical applicationsSERS combined with other analytical techniquesBiophysical applications Life science applications including various microscopies
Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists.
Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor–in–Chief of the Journal of Raman Spectroscopy. 

Spis treści:
Preface.
List of Contributors.
1 Basic Electromagnetic Theory of SERS (Pablo G. Etchegoin and Eric C. Le Ru).
1.1 Introduction.
1.2 Plasmon Resonances and Field Enhancements.
1.3 Field Enhancement Distribution and Localization.
1.4 Electromagnetic Model for the SERS and Fluorescence Enhancement Factors.
1.5 The Magnitude of the SERS Enhancement Factor in Typical Cases.
1.6 Conclusions.
References.
2 Nanoparticle SERS Substrates (Yuling Wang and Erkang Wang).
2.1 Introduction.
2.2 Preparation and Stability of Metal Nanoparticle Colloidal SERS Substrates.
2.3 Characterization of Nanoparticle–Based SERS Substrates.
2.4 Nanoparticles on the Unfunctionalized Solid Surface as SERS Substrates.
2.5 Conclusion and Outlook.
References.
3 Quantitative SERS Methods (Steven E.J. Bell and Alan Stewart).
3.1 Introduction.
3.2 SERS Media.
3.3 Stability and Shelf Life.
3.4 Reproducibility and Internal Standards.
3.5 Selectivity.
3.6 Conclusion.
References.
4 Single–Molecule– and Trace Detection by SERS (Nicholas P.W. Pieczonka, Golam Moula, Adam R. Skarbek, and Ricardo F. Aroca).
4.1 Introduction.
4.2 Experiments and Results.
4.3 Conclusions.
References.
5 Detection of Persistent Organic Pollutants by Using SERS Sensors Based on Organically Functionalized Ag Nanoparticles (Luca Guerrini, Patricio Leyton, Marcelo Campos–Vallette, Concepción Domingo, José V. Garcia–Ramos, and Santiago Sanchez–Cortes).
5.1 Introduction.
5.2 Inclusion Hosts.
5.3 Contact Hosts.
5.4 Occlusion Hosts.
5.5 Conclusions.
Acknowledgements.
References.
6 SERS and Pharmaceuticals (Simona Cîntâ Pînzaru and Ioana E. Pavel).
6.1 Introduction.
6.2 SERS of Antipyretics and Analgesics.
6.3 SERS of Antimalarials.
6.4 SERS of Anticarcinogenics and Antimutagenics.
6.5 Concluding Remarks.
References.
7 SERS and Separation Science (Alison J. Hobro and Bernhard Lendl).
7.1 Introduction.
7.2 SERS and Capillary Electrophoresis (CE).
7.3 SERS and Liquid Chromatography (LC).
7.4 SERS and Gas Chromatography (GC).
7.5 SERS and Thin Layer Chromatography (TLC).
7.6 Other Separation Methods.
7.7 Conclusions.
References.
8 SERS and Microfluidics (Thomas Henkel, Anne März, and Jürgen Popp).
8.1 Introduction.
8.2 Lab–on–a–chip Technology.
8.3 Microfluidic Platforms and Application for SERS.
8.4 Summary.
References.
9 Electrochemical SERS and its Application in Analytical, Biophysical and Life Science (Bin Ren, Yan Cui, De–Yin Wu, and Zhong–Qun Tian).
9.1 Electrochemical Surface–Enhanced Raman Spectroscopy.
9.2 Features of Electrochemical Surface–Enhanced Raman Spectroscopy.
9.3 Experimental Techniques of EC–SERS.
9.4 Applications of EC–SERS.
9.5 Perspectives.
Acknowledgements.
References.
10 Electro n Transfer of Proteins at Membrane Models (Peter Hildebrandt, Jiu–Ju Feng, Anja Kranich, Khoa H. Ly, Diego F. Martín, Marcelo Martí, Daniel H. Murgida, Damián A. Paggi, Nattawadee Wisitruangsakul, Murat Sezer, Inez M. Weidinger, and Ingo Zebger).
10.1 Introduction.
10.2 Model Membranes and Membrane Models.
10.3 Methods for Probing Electron Transfer Processes of Cytochrome c at Coated Electrodes.
10.4 The Unusual Distance Dependence of the Interfacial Electron Transfer Process.
10.5 Electron Transfer and Protein Orientational Dynamics.
10.6 Electric Field Effects on the Electron Transfer Dynamics.
10.7 Electron Transfer and Protein Structural Changes.
10.8 Overall Description of the Mechanism and Dynamics of the Interfacial Processes.
10.9 Interfacial Electric Fields and the Biological Functions of Cytochrome c.
References.
11 Quantitative DNA Analysis Using Surface–Enhanced Resonance Raman Scattering (Ross Stevenson, Karen Faulds, and Duncan Graham).
11.1 Introduction.
11.2 SERRS Surfaces.
11.3 Raman Reporters.
11.4 SERRS DNA Probes.
11.5 Sensitivity.
11.6 Multiplexing.
11.7 Assays.
11.8 Conclusion.
References.
12 SERS Microscopy: Nanoparticle Probes and Biomedical Applications (Sebastian Schlücker).
12.1 Introduction.
12.2 SERS Nanoparticle Probes.
12.3 Biomedical Applications of SERS Microscopy.
12.4 Summary and Outlook.
Acknowledgement.
References.
13 1–P and 2–P Excited SERS as Intracellular Probe (Janina Kneipp).
13.1 From Tags to Probes: Challenges in Intracellular Probing.
13.2 Probing of Intracellular Parameters.
13.3 Surface–Enhanced Hyper Raman Scattering and Its Potential in Studies of Cells.
Acknowledgements.
References.
14 Surface– and Tip–Enhanced CARS (Taro Ichimura and Satoshi Kawata).
14.1 Introduction.14.2 CARS: Coherent Anti–Stokes Raman Scattering.
14.3 Local Enhancement of CARS by Metallic Nanostructures.
14.4 Surface–Enhanced CARS.
14.5 Tip–Enhanced CARS.
References.
Index.

Nota biograficzna:
Sebastian Schlucker obtained his undergraduate and PhD degrees at the University of Wurzburg, Germany. After a postdoctoral stay at the US National Insitute of Health (NIH), Bethesda, Maryland, USA from 2002 till 2004, he completed his habilitation in 2006 at the University of Wurzburg. He has been Professor of Experimental Physics at the University of Osnabruck, Germany since 2008.

Okładka tylna:
Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface–enhanced Raman scattering (SERS) for solving real world problems.
From the contents:Theory and practice of SERSAnalytical applicationsSERS combined with other analytical techniquesBiophysical applications Life science applications including various microscopies
Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists.
Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor–in–Chief of the Journal of Raman Spectroscopy.