Catalytic Asymmetric Conjugate Reactions

This unique and long–awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P–N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.

Spis treści:
Organoboron Reagents in Enantioselective Conjugate Additions (ECA)
Organozinc Reagents: Catalysis
Catalytic ECAs of Grignard Reagents, Organolithium Reagents and Examples of Cu–Catalyzed ECAs
Asymmetric Bifunctional Catalysis Using Heterobimetallic and Multimetallic Systems in Enantioselective Conjugate Additions
Enamines in Catalytic ECAs
Iminium Activation in Catalytic ECAs
Organocatalytic ECAs of Heteroatoms to Alpha, Beta–Unsaturated Carbonyl Compounds
Domino Reactions Involving Catalytic ECAs
Epoxidations
Catalytic Asymmetric Baylis–Hillman Reactions and Surroundings

Nota biograficzna:
Armando Córdova is a researcher at the department of Organic Chemistry at the Arrhenius Laboratory at Stockholm University. Having obtained his M.Sc. in Chemical Engineering 1995 and Ph.D. 1998 at the Royal Institute of Technology (KTH) in Stockholm he took an appointment at the Swedish Pulp and Paper Research Institute (STFI). After six months he took a two–year leave for postdoctoral research at the Scripps Research Institute (TSRI) in La Jolla, U.S.A. After completion of his post–doctoral stay he continued research at TSRI for two more years and in 2003 he returned to Stockholm University in Sweden . In 2004, he became associate Professor at the department of Organic Chemistry at the Arrhenius Laboratory in Stockholm. Prof. Córdova has authored over 100 scientific publications and is the inventor of 10 patents or patent applications. He has also recieved several awards for his reserach including the Tage Erlander Prize given by the Swedish Royal Academy of Sciences (2006), the King Carl XVI Gustaf′s 50–year foundation award (2007), the City of Stockholm´s inventor award (2007). Prof. Córdova is also founder of the chemical company OrganoClick AB.