Artificial Receptors for Chemical Sensors

The first to provide systematically organized information on all three important aspects of artificial receptor design, this book brings together knowledge on an exceptionally hot and multidisciplinary field of research. Strong emphasis is placed on the methodology for discovering artificial receptors, with both definitions for chemosensitivity as well as experimental setups supplied. There follows coverage of numerous classes of artificial receptors, including synthesis, immobilization on surfaces, and quantitative data on properties. The third part of the book focuses on receptor arrays for artificial nose and tongue applications and the whole is rounded off with an outlook and an appendix with all relevant quantitative data on artificial receptors.

Spis treści:
Introduction –
Why Artificial Receptors?
PART I –
MODERN METHODS FOR ARTIFICIAL RECEPTOR DISCOVERY
Quantitative Characterization of Affinity
Selectivity of Artificial Receptors
Combinatorial Development of Chemosensors
PART 2 –
MOLECULAR RECEPTORS
Cyclodextrins
Crown Ethers with Affinity for Organic Compounds
Calixarenes
Boronic Acids
Molecular Receptors for Peptides
Organotin Receptors
Macrocyclic Chiral Selectors
Synthetic Analogues of the Avidin–Biotin System
Cyclophanes
Cryptophanes
Speleands
Acyclic Receptors
PART 3 –
RECEPTORS FORMED BY POLYMERS OR ORGANIZED MOLECULE GROUPS
Molecularly Imprinted Polymers
Aptamers
Nucleic Acids and Analogues
Short Peptides as Receptors
PART 4 –
RECEPTORS FOR ARTIFICIAL NOSES AND TONGUES
Highly Selective Analysis with Poorly Selective Receptors
Polymeric Receptors
Spreader–bar Systems
Conductive Polymers
Inorganic Gas Sensors
Supramolecular Sensor Arrays for Anions
Artificial Receptor Arrays for Protein Recognition
OUTLOOK
APPENDIX –
Quantitative Data on Artificial Receptors: Binding Con stants, Selectivity Constants, Kinetic Constants of Association and Dissociation

Nota biograficzna:
Vladimir M. Mirsky is Professor at Regensburg University, Germany. He graduated from Moscow Medical University in 1981 as M.D. in biophysics and went on to study physical chemistry and electrochemistry at the Frumkin Institute of Electrochemistry of the Soviet Academy of Sciences, obtaining his Ph.D. in 1986. He subsequently held an Alexander–von–Humboldt Research Fellowship and a research position at the CNRS Centre of Molecular Biology in France prior to joining the Institute of Analytical Chemistry at Regensburg University in 1995. He editor of two recent books, "Ultrathin Electrochemical Chemo– and Biosensors" and "Combinatorial Methodologies for Development of Chemical and Biological Sensors". His work has led to 18 patents and patent applications as well as some 100 peer–reviewed scientific papers.
Anatoly K. Yatsimirsky is Professor of chemistry at the National Autonomous University of Mexico in Mexico City. He obtained his Ph.D. and Dr. Sc. degrees from Moscow Lomonosov State University, where he was Professor prior to his move to Mexico in 1992.
He spent Visiting Scholar/Professor stays at Milan University, Italy, in 1980/81 and at the University of California at Santa Barbara in 1998/99. His research is focused on physical organic chemistry and metal complex catalysis and he is the author of 160 peer–reviewed scientific publications including a monograph "Principles and Methods in Supramolecular Chemistry" by John Wiley & Sons and further book contributions.