Amino Acids, Peptides and Proteins in Organic Chemistry: Building Blocks, Catalysis and Coupling Chemistry

Closing a gap in the literature, this is the only book series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who′s who" in amino acid research, this series is a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures.

Spis treści:
AMINO ACIDS AS BUILDING BLOCKS
Alpha–Amino Acid Biosnythesis (Proteinogenic and Non–Proteinogenic)
Heterocycles from Amino Acids
Radical Synthetic Methods for Alpha–Amino Acids
Enzymatic or Microbial Beta–Lactam Synthesis
AMINO ACID COUPLING CHEMISTRY
Solution Phase Peptide Synthesis
Solid Phase Peptide Synthesis: Historical Aspects
Solid Phase Peptide Synthesis: Linkers
Solid Phase Peptide Synthesis: The Fmoc Methodology 1
Solid Phase Peptide Synthesis: The Fmoc Methodology 2
Solid Phase Peptide Synthesis: SPPS Strategies
Coupling Reagents
Chemical Ligation
Automation of Peptide Synthesis
Peptide Purification
Difficlt Peptides


Nota biograficzna:
Andrew Hughes is a Reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post–doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley′s group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.