Ion Chromatography

This separation method is increasingly finding applications in environmental, food, pharmaceutical and clinical analysis.
The completely revised and updated fourth edition of this best–selling classic is a thorough treatment of the subject while remaining concise and readable. Alongside ion exchange resins, detectors, ion chromatographic separations, anion, cation and ion exclusive chromatography, special techniques and chemical speciation, new additions include capillary electrophoresis, monolithic columns, zwitterion columns, DNA/RNA analysis, fundamentals of the science of IC, and micro methods.
The whole is rounded off by handy tables with details on, among others, detection or elution conditions, making this a ready reference for analytical, environmental and food chemists, chromatographers, pharmaceutists, and chemists working in trace analysis.

Spis treści:
INTRODUCTION AND OVERVIEW.
Introduction.
Historical Development.
Principles of Ion Chromatographic Separation and Detection.
INSTRUMENTATION.
Components of an Ion Chromatograph (IC) Instrument.
General Considerations.
Eluent.
Pump.
Sample Injector.
Columns.
Suppressor.
Detector.
Data Acquisition and Calculation of Results.
RESINS AND COLUMNS.
Introduction.
Polymeric Resins.
Resins and Columns for Ion Chromatography.
Anion Exchangers.
Cation Exchangers.
Other Resins.
DETECTORS.

Introduction.
Conductivity Detectors.
Ultraviolet–Visible (UV–Vis) Detectors.
Fluorescence Detector.
Electrochemical Detectors.
Refractive Index Detector.
Evaporative Light Scattering Detector (ELSD).
Other Detectors.
PRINCIPLES OF ION CHROMATOGRAPHIC SEPARATIONS.
General Considerations.
Chromatographic Terms.
Selectivity.
Chromatographic Efficiency.
ANION CHROMATOGRAPHY.
Scope and Conditions for Separation.
Suppressed Anion Chromat ography.
Nonsuppressed Ion Chromatography.
Coated Columns.
Optical Absorbance Detection.
Detection.
Pulsed Amperometric Detector (PAD).
Evaporative Light Scattering Detector (ELSD).
Inductively Coupled Plasma Methods (ICP).
CATION CHROMATOGRAPHY.
Introduction.
Columns.
Separations.
Effect of Organic Solvents.
Separation of Metal Ions with a Complexing Eluent.
Chelating Ion–Exchange Resins and Chelation Ion Chromatography.
ION–EXCLUSION CHROMATOGRAPHY.

Principles.
Separation of Organic Acids.
Simultaneous Determination of Anions and Cations.
Conclusions.
Determination of Carbon Dioxide and Bicarbonate.
Separation of Bases.
Determination of Water.
Separation of Saccharides and Alcohols.
ION PAIR CHROMATOGRAPHY.
Principles.
Typical Separations.
Mechanism.
ZWITTERION STATIONARY PHASES.
Introduction.
Simultaneous Separation of Anions and Cations.
Separation of Anions.
Separation of Cations.
Mechanism.
CAPILLARY ELECTROPHORESIS.
Introduction.
Principles.
Electroosmotic Flow (EOF).
Separations of Ions.
Capillary Electrophoretic Ion Chromatography.
DNA AND RNA CHROMATOGRAPHY.
Introduction.
DNA and RNA Chemical Structure and Properties.
DNA and RNA Chromatography.
Temperature Modes of DNA and RNA Chromatography.
Instrumentation.
Applications of DNA Chromatography.
Applications of RNA Chromatography.
SAMPLE PRETREATMENT.
Dilute and Shoot or Pre–Treat the Sample?
Particulate and Column–Contaminating Matter.
Preconcentration.
Sample Pretreatment.
METHOD DEVELOPMENT AND VALIDATION.
Choosing a Method.
Some Applications of Ion Chromatography.
Statistical Evaluation of Data.
Validation of Analytical Procedures.
CHEMICAL SPECIATION.

Introduction.
Detection.
Chromatography.
Valveless Injection IC.
Specia tion of Some Elements.

Nota biograficzna:
After having obtained his Ph.D. in 1948 by the University of Illinois, Professor James S. Fritz became Senior Chemist and Professor of Chemistry at Iowa State University in 1960. He was named Distinguished Professor in Liberal Arts and Sciences in 1990. Besides Ion Chromatography his research interests are titrations, solid–phase extractions, capillary electrophoresis and analytical complexing reagents. He has authored or coauthored several scientific books, including Fritz and Gjerde′s "Ion Chromatography", now in its 4th printing. In addition, he has published more than 325 scientific publications.
Douglas T. Gjerde received his PhD in analytical chemistry from Iowa State University. After having worked in large and small companies for a number of years, Gjerde founded Sarasep, Inc. in 1990 for the commercialization of polymeric separation technologies and co–founded Transgenomic, Inc. in 1997 for the commercialization of nucleic acid separation technology. He is now working on his third start–up company, PhyNexus, Inc. PhyNexus produces miniaturized sample preparation tools for the biological research market. Gjerde has authored and coauthored numerous articles, book chapters and 5 books and holds over fifty patents in separation science.


Okładka tylna:
This separation method is increasingly finding applications in environmental, food, pharmaceutical and clinical analysis.
The completely revised and updated fourth edition of this best–selling classic is a thorough treatment of the subject while remaining concise and readable. Alongside ion exchange resins, detectors, ion chromatographic separations, anion, cation and ion exclusive chromatography, special techniques and chemical speciation, new additions include capillary electrophoresis, monolithic columns, zwitterion columns, DNA/RNA analysis, fundamentals of the science of IC, and micro me thods.
The whole is rounded off by handy tables with details on, among others, detection or elution conditions, making this a ready reference for analytical, environmental and food chemists, chromatographers, pharmaceutists, and chemists working in trace analysis.