Essential Endocrinology and Diabetes: Includes Desktop Edition

Beautifully presented, and now in full colour, the sixth edition of Essential Endocrinology and Diabetes is fullyup–to–date with the latest knowledge and concepts on theworkings of the endocrine system. It explains the key principles ofendocrine physiology in an easy reading style popular withstudents, clinicians and scientists. The invaluable background onbasic science and investigation, including new moleculartechniques, provides the foundation for detailed discussion ofthe diagnosis and management of clinical endocrine disorders anddiabetes.

The teaching style and presentation has been strengthenedthroughout, and includes learning objectives and recap links at the beginning of each chapter thatremind the reader of key findings and principles, whilecross–referencing makes it easy to locate related informationquickly and efficiently. There are also more case studies, withdetailed answers applying theory to practice.

Essential Endocrinology and Diabetes is the perfectresource for a course on endocrinology and diabetes, as partof USMLE teaching, and an on–going companion during postgraduateclinical and scientific study. It is accompanied by a FREEenhanced Wiley Desktop Edition – the interactive, digital versionof the book – featuring downloadable text and images,highlighting and note taking facilities, book–marking,cross–referencing, in–text searching, and linking to references andglossary terms.

Preface vii

List of abbreviations x

How to get the best out of your textbook xii

PART 1: Foundations of Endocrinology 1

1 Overview of endocrinology 3

2 Cell biology and hormone synthesis 14

3 Molecular basis of hormone action 27

4 Investigations in endocrinology and diabetes 48

PART 2: Endocrinology Biology to Clinical Practice63

5 The hypothalamus and pituitary gland 65

6 The adrenal gland 99

7 Reproductive endocrinology 127

8 The thyroid gland 165

9 Calcium and metabolic bone disorders 190

10 Pancreatic and gastrointestinal endocrinology and endocrineneoplasia 213

PART 3: Diabetes and Obesity 233

11 Overview of diabetes 235

12 Type 1 diabetes 257

13 Type 2 diabetes 285

14 Complications of diabetes 311

15 Obesity 343

Index 360

Richard Holt is Professor in Diabetes and Endocrinology atthe University of Southampton School of Medicine and HonoraryConsultant in Endocrinology at Southampton University Hospitals NHSTrust. He is also a Fellow of the Higher Education Academy.

Neil Hanley is Professor of Medicine and Wellcome TrustSenior Fellow in Clinical Science at the University of Manchester.He is Honorary Consultant in Endocrinology at the CentralManchester University Hospitals NHS Foundation Trust, and Directorof the Academy for Training & Education at the ManchesterBiomedical Research Centre.

"Essential Endocrinology has been a brilliant book for mygeneral medicine placement. It is concise and well–illustrated, andits handy size means it is not a hassle to carry it when away inregional hospitals. The case histories have been a particularlyuseful feature of the book to test my understanding ofendocrinology in a clinically relevant manner. I feel the contentof the book is pitched perfectly for medical students.

Recently I have had to teach the topics of adrenal and thyroidhormones and the clinical applications to preclinical students.This book has been particularly useful during preparation, as itdedicates 2 chapters specifically to them. It covers the physiologyin good detail without being excessive. Perhaps in a futureedition, there could be a page or two in each chapter dedicated tothe relevant histology since this is something that would berelevant to preclinical students and the book is recommended as thecore text for second year med students studying endocrinology atCambridge." (Medical student supervisor, CambridgeUnversity)

I love this book, it is everything I am currently lookingfor as a 5th year about to sit finals, and I will be reading everychapter in preparation.   (Final year medicalstudent, University of Glasgow)

I am very impressed at the ease with which I am readingsome of the hardest material especially the molecular basisof endocrinology (Psychiatry Resident, University ofCincinnati)