Magnetic Resonance Imaging in Tissue Engineering

Provides a unique overview of the field of non–invasive magnetic resonance assessment of tissue engineering and regenerative medicine

Groundbreaking work in tissue engineering and regenerative medicine is paving the way for the repairing and/or replacing biological tissues and organs.  Engineers, scientists and physicians work together in this field to use biomaterials and cells as the building blocks for new life.  One of the newest and most exciting areas of tissue engineering is the incorporation of bio–inspired cues into scaffolds through techniques such as patterning of topographies and adhesive ligands.  These cues can influence cellular functions, including differentiation, in new ways that are being discovered every day and are paving the way for cutting edge clinical breakthroughs in areas such as cardiovascular tissue engineering, bone repair and organ regeneration.

Magnetic Resonance in Tissue Engineering is designed to provide in–depth analysis of advances made in the MR assessment of tissue engineering applications during the last decade. Since engineered tissues and tumors share the common characteristics of high cell density combined with fast and abrupt ECM growth, and because the MR tools used in tumor imaging can also be applied for tissue engineering applications, the book also contains a few chapters on tumor imaging using magnetic resonance. The book features: 

Comprehensive details of magnetic resonance spectroscopy (NMR) and imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs New techniques to assess engineered tissues Cell–based therapies, engineered cartilage, bone, musculoskeletal, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by NMR/MRI Chapters on tumor imaging methods to provide complimentary information for tissue engineering and imaging experts.

Magnetic Resonance in Tissue Engineering contains chapters from leading experts working to developing robust functional engineered tissues as well as analytical experts developing new techniques to assess engineered tissues. This rare interdisciplinary project is developed to bridge a gap in current offerings. Readers from both the tissue–engineering and imaging backgrounds will find this interdisciplinary material useful in their research.

Mrignayani Kotecha is currently affiliated with the Department of Bioengineering at the University of Illinois at Chicago as an adjunct assistant professor. In this position, she is developing proton and sodium magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) techniques for monitoring the growth of musculoskeletal engineered tissues. Her broad research interests include the application of multinuclear magnetic resonance techniques to biomedical engineering problems.

Richard L. Magin is currently a Professor of Bioengineering at University of Illinois at Chicago and directs the Diagnostic NMR Systems Laboratory. Professor Magin is a Fellow of the IEEE and AIMBE, and former Editor of the Critical Reviews in Biomedical Engineering. In 2012 he was designated a Distinguished Professor of Bioengineering at UIC.  His research interests focus on the applications of magnetic resonance imaging (MRI) in science and engineering.

Jeremy J. Mao is currently professor at Columbia University and also Edwin Robinson Endowed Chair. Dr. Mao s research team has been at Columbia for the past 7 years and made several important discoveries including a cover article in the Lancet.  In addition, Dr. Mao s work has been published in Nature Medicine, Lancet, Cell Stem Cell, JCI, etc.   All together Dr. Mao has published over 260 scientific papers and proceedings, and written 2 books. Dr. Mao s research has led to over 70 patents and establishment of 2 biotechnology companies. Dr. Mao has received a number of prestigious awards including Yasuda award and Spanadel Award.