Physiological Control Systems: Analysis, Simulation, and Estimation

A guide to key control principles and how they are used to characterize a variety of physiological mechanisms

The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications of linear and nonlinear dynamic analyses to physiology, parameter estimation methods, and adaptive estimation and control. The author a noted expert in the field includes a wealth of worked examples that illustrate key concepts and methodology and offers in–depth analyses of selected physiological control models that highlight the topics presented.

The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on basic control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource:

Offers new sections that explore identification of nonlinear and time–varying systems, and provide the background for understanding the link between continuous–time and discrete–time dynamic models Presents helpful, hands–on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter

Written for biomedical engineering students and biomedical scientists, Physiological Control Systems covers classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.

MICHAEL C.K. KHOO is a Professor of Biomedical Engineering and Pediatrics in the Biomedical Engineering Department at the University of Southern California. He is a fellow of the IEEE, Biomedical Engineering Society, the American Institute of Medical and Biological Engineering, and the International Academy of Medical and Biological Engineering.