Clinical Reproductive Science

The comprehensive and authoritative guide to clinical reproductive science

The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author – a noted expert in the field – focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation.

Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource:

Offers an accessible guide to the most current research and techniques to the science of clinical reproduction Covers the fundamental elements of reproductive science Includes information on male and the female reproductive basics everything from sexual differentiation to foetal development and parturition Explores the long–term health of children conceived through IVF Contains the newest developments in assisted reproductive technology

Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.  

Preface

Section One – Reproductive Science: Fundamentals of Human Reproductive Biology

Chapter 1: Sexual differentiation, gonadal development and development of the external genitalia: A review of the regulation of sexual differentiation
Rebecca M. Perrett

Chapter 2: Male and female reproductive anatomy
Sara Sulaiman and James Coey

Chapter 3: Fundamentals of reproductive endocrinology
Derrick Ebot, Haider Hilal, Michael Carroll and James Coey

Chapter 4: The ovaries, oocytes and Folliculogenesis
Jacques Gilloteaux  and James Coey

Chapter 5: The human Spermatozoa
Allan Pacey and Katrina Williams

Chapter 6: The biology of fertilisation
Michael Carroll

Chapter 7: Human embryo development: From zygote stage to peri–implantation blastocyst
Stephane Berneau and Michael Carroll

Chapter 8: The female reproductive tract and early embryo development: a question of supply and demand
Henry J. Leese and Daniel R. Brison

Section Two – Clinical Reproducctive Science: Causes of Male and Female Infertility 

Chapter 9: Disorders of male reproductive endocrinology
Michael Carroll

Chapter 10: Disorders of female reproductive endocrinology
Mahshid Nickkho–Amiry and Cheryl T. Fitzgerald

Chapter 11: Oocyte aneuploidy and the maternal age effect
Mary Herbert

Chapter 12: Female reproductive pathology: Peritoneal, uterine and fallopian tube pathologies
Kenneth Ma Kin Yue, Rosa Trigas and Edmond Edi–Osagie

Chapter 13: Pathologies of the male reproductive tract
Aarush Sajjad, Muhammad A Akhtar and Yasmin Sajjad

Chapter 14: The impact of infections on reproduction and fertility
Val Edwards Jones

Chapter 15: Nutrition, foetal health and pregnancy
Emma Derbyshire

Chapter 16: The embryonic environment and developmental origins of health
Tom P. Fleming and Congshan Sun

Chapter 17: Lifestyle and environmental impacts on fertility
Ana–Maria Tomova and Michael Carroll

Section Three – Clinical Reproducctive Science in Practice: IVF and Assisted Reproductive Technologies

Chapter 18: Assessing the infertile Couple
Narmada Katakam, Ruth Arnesen, Caroline Watkins, Bert Stewart and Luciano G. Nardo

Chapter 19: Ovarian stimulation protocols
Nikolaos Tsampras and Cheryl T. Fitzgerald

Chapter 20: Oocyte retrieval techniques and culture of oocytes
Dawn Yell

Chapter 21: Sperm preparation: strategy and methodology
Stephen Harbottle

Chapter 22: Diagnostic semen analysis: uncertainty, clinical value and recent advances
Mathew Tomlinson

Chapter 23: Surgical sperm retrieval
Muhammad A Akhtar, Elizabeth Hester, Solmaz Gul Sajjad and Yasmin Sajjad

Chapter 24: In vitro fertilization and intracytoplasmic sperm injection
Bryan Woodward

Chapter 25: Morphological assessment of embryos in culture
J.Diane Critchlow

Chapter 26: In vitro culture of gametes and embryos The culture medium
Robbie Kerr

Chapter 27: Incubators in the ART laboratory
Louise Hyslop

Chapter 28: Embryo transfer techniques and improving embryo implantation rates
Rachel Cutting

Chapter 29: Cryopreservation of gametes and embryos
Tope Adeniyi

Chapter 30: Preimplantation genetic diagnosis and screening
Colleen Lynch and Brendan Ball

Chapter 31: Long–term follow–up of children conceived through IVF
Omar Abdel–Mannan and Alastair G Sutcliffe

Index

Dr Michael Carroll, Senior Lecturer in Reproductive Science, School of Healthcare Science, Manchester Metropolitan University, UK