Practical Functional Group Synthesis

Preparing organic architectures containing single or multiple functional groups remains a current and challenging goal for the synthetic community due to the myriad of applications the resulting compounds have in organic, inorganic, polymer, materials, and pharmaceutical chemistry. The demand for readily accessible synthetic intermediates, efficient solar cells, smart polymers, and drugs with increased potency and fewer side effects is expected to rise in the coming years.

Practical Functional Group Synthesis addresses the chemists working in these fields by offering a practical guide to modern functional group synthesis through carbon–heteroelement bond forming reactions. Rather than spread coverage thin, the author focuses on the 5 most common and used heteroelements thus, maintaining a focus on chemical reactions that result in the formation of nitrogen, oxygen, phosphorus, sulfur or boron bonds. Each chapter centers on a single type of heteroelement, with subsections discussing specific functional groups. Those subsections contain the detailed information needed to facilitate the selection of ideal reaction conditions in order to prepare specific functional groups.

A valuable handbook for chemists performing bond forming reactions, this book features:

    Guidance for carrying out modern functional group synthesis for chemists involved in the creation of new drugs, materials, or synthetic intermediates
    Coverage of emerging topics like sustainability and microwave / ultrasound processing
    Key and recent developments which are otherwise scattered across journal literature into a single source
    Chemical equations to assist readers and mechanistic details of the transformations

Robert A. Stockland, PhD, is an Associate Professor of Chemistry at Bucknell University, where he regularly teaches on topics of organic and inorganic chemistry and where his research focuses on the development of synthetic methodology. Among his publications, Dr. Stockland has a number of leading journal papers and co–edited a symposium book.