Allergy and Clinical Immunology

The Mount Sinai Expert Guides provide quick access to point–of–care specialist clinical information for physicians across a range of therapeutic areas.

For each specialty area, the guides emphasize:

Common pitfalls in diagnosis and management

How to prevent complications

Diagnostic and treatment algorithms

Key scientific trials

Evidence–based clinical content

Major society guidelines in order to summarize the very latest in diagnosis and management of diseases and related symptoms.

Edited by renowned specialists from the Icahn School of Medicine at Mount Sinai, key faculty members provide the content for all chapters. To ensure consistency within each book and the series as a whole, chapters follow a unified structure throughout.

Bonus features such as online case studies with related questions for self–assessment, key patient advice, and  ICD codes are provided via the series companion website.

Each guide also has its own mobile app available for  purchase, allowing you rapid access to the key features wherever you may be.

Contributors, ix

Series Foreword, xi

Preface, xii

List of Abbreviations, xiii

About the Companion Website, xvii

Part 1: Allergy

1 Atopic Dermatitis in Infants and Young Children, 3
Jean ]Christoph Caubet and Anna Nowak ]We grzyn

2 Atopic Dermatitis in Teenagers and Adults, 15
Saakshi Khattri and Emma Guttman ]Yassky

3 Contact Dermatitis, 25
Mariya Rozenblit and Emma Guttman ]Yassky

4 Allergic Rhinitis, 36
Supinda Bunyavanich

5 Non ]Allergic Rhinitis, 44
Beth E. Corn

6 Sinusitis, 52
Yan W. Ho and Satish Govindaraj

7 Allergic Diseases of the Eye, 66
Amanda L. Cox

8 Tests for Assessing Asthma, 77
Gwen S. Skloot

9 Asthma in Infants and Children, 82
Kate Welch and Jennifer S. Kim

10 Asthma in Teenagers and Adults, 91
Supinda Bunyavanich

11 Evaluation of Cough, 98
Paula J. Busse

12 Exercise ]Induced Asthma, 107
Supinda Bunyavanich

13 Occupational Asthma, 114
Paula J. Busse

14 Status Asthmaticus and Pending Pulmonary Failure, 123
Jacob D. Kattan

15 Evaluation of Food Allergy, 132
Scott H. Sicherer

16 Oral Allergy Syndrome, 140
Julie Wang

17 Food Allergy and Atopic Dermatitis, 148
Kate Welch and Hugh A. Sampson

18 Food Protein ]Induced Enterocolitis Syndrome, 155
Elizabeth J. Feuille and Anna Nowak ]We grzyn

19 Food Protein ]Induced Proctocolitis Syndrome, 165
Jean ]Christoph Caubet and Anna Nowak ]We grzyn

20 Eosinophilic Esophagitis, 173
Mirna Chehade

21 Eosinophilic Gastroenteritis, 183
Mirna Chehade

22 Food Allergy ]Induced Anaphylaxis, 191
Kate Welch and Hugh A. Sampson

23 Adverse Reactions to Food and Drug Additives, 200
Julie Wang

24 Celiac Disease, 208
Mirna Chehade

25 Oral Food Challenges (Procedure), 217
Hugh A. Sampson

26 Acute Urticaria, 222
Amanda L. Cox

27 Chronic Urticaria, 235
Julie Wang

28 Hereditary Angioedema, 245
Paula J. Busse

29 Anaphylaxis, 256
Jacob D. Kattan

30 Mastocytosis, 267
Amanda L. Cox

31 Insect Sting Allergy, 278
Scott H. Sicherer

32 Latex Allergy, 288
Jennifer S. Kim

33 Allergy to Antibiotics, 294
Jennifer S. Kim

34 Allergy to Non ]Antibiotic Drugs, 301
Jacob D. Kattan

35 Drug Desensitization, 308
Julie Wang

36 Immunotherapy (Procedure), 314
Beth E. Corn

37 Allergy Testing (Procedures: Skin Testing; Blood Tests), 319
Scott H. Sicherer

Part 2: Clinical Immunology

38 Evaluating the Child with Recurrent Infections, 327
Shradha Agarwal

39 Evaluating the Adult with Recurrent Infections, 335
Charlotte Cunningham ]Rundles

40 Antibody Deficiencies, 341
Charlotte Cunningham ]Rundles

41 Selective IgA Deficiency, 348
Shradha Agarwal

42 Severe Combined Immunodeficiency, 355
Kate Welch and Elena S. Resnick

43 Wiskott Aldrich Syndrome, 362
Elena S. Resnick

44 DiGeorge Syndrome, 368
Kate Welch and Elena S. Resnick

45 Chronic Mucocutaneous Candidiasis, 375
Shradha Agarwal

46 X ]linked Immune Dysregulation with Polyendocrinopathy (IPEX) Syndrome, 382
Elena S. Resnick

47 Autoimmune Lymphoproliferative Syndrome, 388
Charlotte Cunningham ]Rundles

48 Hyper IgE Syndrome, 393
Shradha Agarwal

49 Deficiencies of Complement, 402
Paula J. Busse

50 Phagocytic Cell Disorders, 408
Charlotte Cunningham ]Rundles

51 Human Immunodeficiency Virus Infection in Infants, Children, and Adolescents, 415
Gail F. Shust and Roberto Posada

52 Human Immunodeficiency Virus Infection in Adults, 426
Timothy Sullivan and Michael Mullen

53 Infections in the Compromised Host, 435
Charlotte Cunningham ]Rundles

Index, 441

A color plate section appears between pages 206 and 207

Edited by
Hugh A. Sampson, MD
Kurt Hirschhorn Professor of Pediatrics
Dean for Translational Biomedical Sciences. Director, Elliot and Roslyn Jaffe Food Allergy Institute Division of Allergy/Immunology; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Series Editor
Scott L. Friedman MD, Fishberg Professor of Medicine, Dean for Therapeutic Discovery, Chief, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA