Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Volume 2

The ultimate reference guide to the synthesis of radiopharmaceuticals The Radiochemical Syntheses series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step–by–step guidance on how to replicate these syntheses in the laboratory. Volume 2 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. Contributions from leading researchers detail methods and procedures for conducting radiochemical reactions to prepare radionuclides that are used in positron emission tomography (PET) imaging. Highlighted in the book are new approaches to carbon–11 (C11) and fluorine–18 (F18), which are two of the most commonly used radionuclides. The reactions include solid–phase radiochemistry, palladium–catalyzed radiochemistry, microwave radiochemical reactions, click chemistry, and microfluidics. These detailed monographs provide readers the necessary information needed to reproduce these synthetic reactions in their own labs. Readers have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.

Peter J. H. Scott is an Assistant Professor in the Department of Radiology at the University of Michigan Medical School. Dr. Scott edited Linker Strategies in Solid–phase Organic Synthesis (also from Wiley) and is the series editor for the Wiley Series on Solid Phase Organic Syntheses.