Vascular Dementia

Vascular dementia (VAD) accounts for one–third of all dementias in today′′s aging population, second only to Alzheimer′s disease (DAT). Fortunately, current imaging techniques allow clinicians to view specific lesions in the brain, classify them by etiology and anatomical location, and assess changes using serial imaging, while at the same time correlating those changes with signs and symptoms of VAD or DAT. In 17 chapters, this book summarizes new concepts concerning the epidemiology, etiology, risk factors, neuropathology and pathogenesis of VAD and DAT, and mixtures of the two, and reviews their multiple causes, including microvascular and hemorrhagic lesions, and ischemic and inflammatory changes affecting both white and gray matter.
For the first time, the subject of reversible cognitive decline among the elderly is described, and early control of vascular risk factors are described that can improve early cognitive decline and prevent strokes and dementia.
Vascular dementia (VAD) accounts for one–third of all dementias in today′′s aging population, second only to Alzheimer′′s disease (DAT). Fortunately, current imaging techniques allow clinicians to view specific lesions in the brain, classify them by etiology and anatomical location, and assess changes using serial imaging, while at the same time correlating those changes with signs and symptoms of VAD or DAT. In 17 chapters, this book summarizes new concepts concerning the epidemiology, etiology, risk factors, neuropathology and pathogenesis of VAD and DAT, and mixtures of the two, and reviews their multiple causes, including microvascular and hemorrhagic lesions, and ischemic and inflammatory changes affecting both white and gray matter.
For the first time, the subject of reversible cognitive decline is described in detail, and early control of vascular risk factors are discussed that can improve, prevent or reverse early cognitive decline an d prevent strokes and dementia. Clinical features of patients with VAD are compared to those with DAT, so that similarities and differences in the clinical course of both diseases are apparent. Simple and practical methods for assessing and quantifying cognitive and neurobehavioral deteriorations are discussed, as well as issues for prevention and therapy.
Neurologists, vascular surgeons, internists, family practitioners, nurses, rehabilitationists and clinical psychologists will all find this text practical, useful and informative.

Spis treści:
Contributors.
Foreword.
James F. Toole, M.D., President of World Federation of Neurology.
Preface.
John S. Meyer, Gaiane M. Rauch, Helmut Lechner, Carlo Loeb, James F. Toole.
Chapter 1 – Epidemiology of Vascular Dementia.
Md. Anwarul Haque, John S. Meyer, Gaiane M. Rauch.
Chapter 2 – Cardiovascular Risk Factors Contributing to Cerebral Degenerative Changes, Cognitive Decline and Dementia.
John S. Meyer, Gaiane M. Rauch, Ronald A. Rauch.
Chapter 3 – Risk Factors For Vascular Dementia.
Helmut Lechner.
Chapter 4 – Neuropathological Correlates of Vascular Dementia.
Carlo Loeb.
Chapter 5 – Microvascular Pathology In Vascular And Related Dementias.
Alberto Portera–Sanchez, Jesús Porta–Etessam.
Chapter 6 – Recent Advances in Vascular Dementia Research.
David W. Desmond.
Chapter 7 – Clinical Features Of Patients With Vascular Dementia Versus Alzheimer′s Disease.
Gaiane M. Rauch, John S. Meyer.
Chapter 8 – Neuropsychological Assessments For Cognitive Decline.
Md. Anwarul Haque, John S. Meyer, Gaiane M. Rauch.
Chapter 9 – Subcortical Arteriosclerotic Encephalopathy Binswanger Type or Chronic Microvascular Leukoencephalopathy Syndrome.
Carlo Loeb.
Chapter 10 – Criteria For Diagnosis Of Vascular Dementia.
Carlo Loeb, John S. Meyer, Gaiane M. Rauch.
Chapter 11 – Classification Of Subtypes Of Vascular Dementia Including Subcortical Versus Cortical Dementias.
John S. Meyer, Gaiane M. Rauch.
Chapter 12 – Neuroimaging in Vascular Dementia.
John S. Meyer, Gaiane M. Rauch, Ronald A. Rauch.
Chapter 13 – Clinical Observation During Long–Term Follow–Up of Outcome in.
Vascular Dementia.
Helmut Lechner, Gotz Bertha.
Chapter 14 – Prevention and Treatment of Vascular Dementia.
John S. Meyer, Gaiane M. Rauch.
Chapter 15 – Scientific Basis for Plasmapheresis in Vascular Dementia.
Helmut Lechner.
Chapter 16 – Estrogen Therapy For Prevention Of Dementia In Post–Menopausal Women.
Gaiane M. Rauch, John S. Meyer.
Chapter 17 – Factors Influencing Long–Term Survival Among Patients With Vascular Dementia Versus Alzheimer′s Disease.
John S. Meyer, Gaiane M. Rauch.
Index

Okładka tylna:
Vascular dementia (VAD) accounts for one–third of all dementias in today′′s aging population, second only to Alzheimer′s disease (DAT). Fortunately, current imaging techniques allow clinicians to view specific lesions in the brain, classify them by etiology and anatomical location, and assess changes using serial imaging, while at the same time correlating those changes with signs and symptoms of VAD or DAT. In 17 chapters, this book summarizes new concepts concerning the epidemiology, etiology, risk factors, neuropathology and pathogenesis of VAD and DAT, and mixtures of the two, and reviews their multiple causes, including microvascular and hemorrhagic lesions, and ischemic and inflammatory changes affecting both white and gray matter.
For the first time, the subject of reversible cognitive decline among the elderly is described, and early control of vascular risk factors are described that can improve early cognitive decline and prevent strokes and dementia.
Vascular dementia (VAD) accounts for one–third of all dementias in today′′s aging population, second only to Alzheimer′′s disease (DAT). Fortunately, current imaging techniques allow clinicians to view specific lesions in the brain, classify them by etiology and anatomical location, and assess changes using serial imaging, while at the same time correlating those changes with signs and symptoms of VAD or DAT. In 17 chapters, this book summarizes new concepts concerning the epidemiology, etiology, risk factors, neuropathology and pathogenesis of VAD and DAT, and mixtures of the two, and reviews their multiple causes, including microvascular and hemorrhagic lesions, and ischemic and inflammatory changes affecting both white and gray matter.
For the first time, the subject of reversible cognitive decline is described in detail, and early control of vascular risk factors are discussed that can improve, prevent or reverse early cognitive decline and prevent strokes and dementia. Clinical features of patients with VAD are compared to those with DAT, so that similarities and differences in the clinical course of both diseases are apparent. Simple and practical methods for assessing and quantifying cognitive and neurobehavioral deteriorations are discussed, as well as issues for prevention and therapy.
Neurologists, vascular surgeons, internists, family practitioners, nurses, rehabilitationists and clinical psychologists will all find this text practical, useful and informative.