Biomaterials and Medical Device - Associated Infections

Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection.

Provides analysis of biofilms and their relevance to implant associated infections.Assesses technologies for controlling biofilms.Considers advantages and disadvantages of in vivo infection studies.

Part 1 – Introduction to biomaterials and medical device related infections

1. Introduction to biomaterials and medical device associate infections Ian R. Cooper, University of Brighton, UK

2. Biofilms and implant-associated infections Garry Laverty, Sean P. Gorman, Brendan F. Gilmore, Queens University of Belfast, UK

3. In vivo infection studies Yvonne Achermann, Patrick Kerns, Mark E. Shirtliff, University of Maryland, USA

4. Diagnosis of biofilm-associated infections in medical devices S. Bose and A.K. Ghosh, Pravara Institute of Medical Sciences, India

5. Diagnosis and treatment of implant associated infections M. Al-Mayahi, P. Vaudaux, L. Deabate, A. Lomessy, D. Suvà and I. Uçkay, Geneva University Hospitals and Faculty of Medicine, Switzerland

Part 2 - Technologies and materials for controlling biofilms

6. Surface modification of biomaterials for biofilm control Olha Bazaka and Kateryna Bazaka, James Cook University, Australia

7. Surface nano engineering for combating biomaterials infections K.G. Neoh, National University of Singapore, Singapore

8. Bioactive biomaterials for controlling biofilms B. F. Gilmore and L. Carson, Queen’s University Belfast, UK

9. Antibiotics and cements for the prevention of biofilm associated infections G. Massazza, University of the Studies of Turin, Italy, A. Bistolfi, Adelaide Hospital, Italy , E. Verné and M. Miola, Polytechnic of Turin, Italy, L.Ravera and F. Rosso University of the Studies of Turin, Italy

10. Antibacterial composite restorative materials for dental applications I. M. Mehdawi, Benghazi University, Libya and A. Young UCL Eastman Dental Institute, UK

11. Infection resistant biomaterials Y. Delaviz, J. P. Santerre, D. G. Cvitkovitch , University of Toronto, Canada