Infertility and Assisted Reproduction

Assisted reproductive technology (ART) is available to two-thirds of the world’s population, and world-class experts, representing research from 18 different countries, have contributed to this groundbreaking textbook, detailing the techniques and philosophies behind medical procedures of infertility and assisted reproduction. This is one of the most rapidly changing and hotly debated fields in medicine. Different countries have different restrictions on the research techniques that can be applied to this field, and, therefore, experts from around the world bring varied and unique authorities to different subjects in reproductive technology. Encompassing the latest research into the physiology of reproduction, infertility evaluation and treatment, and assisted reproduction, it concludes with perspectives on the ethical dilemmas faced by clinicians and professionals. This book will be the definitive resource for those working in the areas of reproductive medicine world wide.

Spis treści:
Foreword
Part I. Physiology of Reproduction
1. Folliculogenesis, from prenatal follicles to corpus luteum regression
2. Mechanisms of follicular development, the role of gonadotrophins
3. Human follicle culture in vitro
4. Endometrial receptivity
5. Molecular mechanisms of implantation-
Part II. Infertility Evaluation and Treatment
6. Evaluation of the infertile female
7. Fertiloscopy
8. Microlaparoscopy
9. Pediatric and adolescent gynecological laparoscopy
10. Laparoscopic tubal anastomosis
11. Tubal microsurgery versus assisted reproduction
12. The future of operative laparoscopy for infertility
13. Operative laparoscopy for uterine septum
14. Lasers in reproductive surgery and infertility
15. Ultrasonography of the endometrium for infertility
16. Ultrasonography of the cervix
17. Transrectal ultrasonography in male infertility
18. The basic semen analysis, interpretation and clinical application
19. Evaluation of sperm damage, beyond the WHO criteria
20. Male factor infertility – state of ART
21. Diagnosis and treatment of common ejaculatory disorders in a male infertility practice
22. Ovulation induction
23. Clomiphene citrate and alternatives for ovulation induction
24. Aromatase inhibitors for assisted reproduction
25. Pharmacodynamics and pharmacokinetics of gonadotrophins
26. The future of gonadotrophins
27. Ovarian hyperstimulation syndrome
28. Reducing the risk of high order multiple pregnancy due to ovulation induction
29. Hyperprolactinemia
30. Medical management of PCOS
31. Surgical management of PCOS
32. Endometriosis associated infertility
33. Medical management for endometriosis
34. Reproductive surgery for endometriosis-associated infertility
35. Congenital uterine malformations and reproduction
36. Unexplained infertility
37. Premature ovarian failure (POF), characteristics, diagnosis, and management
Part III. Assisted Reproduction
38. Medical strategies to improve ART outcome, current evidence
39. Surgical preparation of the patient for in-vitro fertilizationy
40. IVF in medically complicated patients
41. Polycystic ovary syndrome and IVF
42. Endometriosis and assisted reproductive technology
43. Evidence-based medicine comparing HMG/FSH and agonist/antagonist and rec/urinary hcg/LH/GnRH to trigger ovulation
44. Luteal phase support in assisted reproduction
45. Thrombophilia
46. Intrauterine insemination
47. The prediction and management of poor responders in ART
48. Oocyte donation
49. In-vitro maturation of oocytes
50. Oocyte and embryo freezing
51. Semen cryopreservation
52. The management of azoospermia
53. Spermatid injection, current status
54. Optimizing embryo transfer
55. Single embryo transfer
56. Blastocyte transfer
57. Clinical significance of embryo multinucleation
58. Quality control in the IVF laboratory
59. Nursing in assisted reproduction
60. Clinical outcomes in ART, can the playing field be made level?
61. Chinese medicine
62. Complications of assisted reproductive technology
63. Ectopic and heterotopic pregnancies from IVF
64. The impact of oxidative stress on female reproduction and ART, an evidence-based review
65. PGD for chromosomal anomalie
66. PGD for monogenic disorders and molecular diseases
67. Epigenetics and ART
68. Congenital abnormalities and assisted reproductive technology
Part IV. Ethical Dilemmas in Fertility and Assisted Reproduction
69. Stem cell research
70. Fertility preservation in male and female patients
71. Ethical dilemmas in ART, current issues
72. Infertility treatment in perimenopausal women, ethical considerations
73. Religious perspectives of ethical issues in ART
74. The future of assisted reproduction.