Growth Hormone in Adults

This revised edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the disorders that result from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject, and this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and its role in ageing and gender-specific effects. This compilation by the world’s leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. The volume is the most authoritative, comprehensive and detailed account available and will be an essential source of reference for all endocrinologists.

Spis treści:
Foreword N. Skakkeback
Part I. Introduction
1. Physiological regulators of growth hormone secretion M. L. Hartman
2. Insulin-like Growth Factors (IGF) and their IGF-binding proteins - their use for diagnosis of growth hormone deficiency W. F. Blum
3. Growth hormone and IGF-I effects on in-vivo substrate metabolism in humans N. Møller
4. Determination of growth hormone and GHBP in serum S. Fisker and H. Ørskov
Part II. Diagnostic and Clinical Aspects
5. The syndrome of growth hormone deficiency in adults R. Cuneo, F. Salomon and P. H. Sönkse
6. The diagnosis of growth hormone deficiency in adults D. M. Hoffman and K. K. Y. Ho
7. Monitoring of growth hormone replacement therapy A. A. Toogood, S. J. Howell and S. M. Shalet
Part III. Growth Hormone Replacement Therapy in Adults with Growth Hormone Deficiency
8. The effect of growth hormone on protein metabolism D. L. Russell-Jones and M. Umpleby
9. Growth hormone deficiency, insulin resistance and glucose metabolism F. L. Hew, M. C. Christopher and F. P. Alford
10. Growth hormone and body composition J. S. Christiansen and N. Vahl
11. Effects of growth hormone on fluid homeostasis J. Møller
12. Growth hormone and cardiac function A. Cittadini, S. Longobardi, S. Fazio and L. Sacià
13. Growth hormone and cardiovascular risk factors T. Rosen
14. Growth hormone and exercise performance muscle strength and sweat production in healthy subjects and in adults with growth hormone deficiency A. Juul, K. Main and N. E. Skakkebaek
15. Growth hormone and bone and mineral metabolism J-M. Kaufman and M. Vandeweghe
16. Growth hormone and thyroid function and energy expenditure J. O. L. Jørgensen, T. Wolthers and J. Weeke
17. Growth hormone and psychosocial and central nervous effects J.-O. Johansson, L. Wirén and B.-Å. Bengtsson
18. Impact of gender and age on growth hormone responsiveness P. Burman and G. Johannsson
Part IV. Growth Hormone, Growth-hormone Releasing Peptides and Ageing
19. Growth hormone and ageing K. G. OConnor and M. R. Blackman
20. Growth hormone releasing substances - basic aspects K. K. McKee, A. D. Howard, S. D. Feighner, S. Pony and R. G. Smith
21. Clinical uses of growth hormone releasing peptides (GHRPs) and GHPR analogues in adults I. M. Chapman and M. O. Thorner
Index.