Memory in Neurodegenerative Disease

This book is the first to review in depth the neurobiological and clinical characteristics of memory and its disorders in neurodegenerative disease. It presents current information about memory disorders in Alzheimer’s, Huntington’s and Parkinson’s diseases and in other neurological conditions such as progressive supranuclear palsy, Creutzfeld–Jacob disease and HIV-associated dementia. The contributors are among the most distinguished working in this field. They present the neuroanatomical and neurochemical basis of memory disorders in neurodegenerative disease, and review the contribution of neuroradiology and neuropathology to the understanding of memory and amnesia. Diagnosis, assessment and treatment issues are discussed, as are ethical and legal considerations and topics of emerging interest such as the early detection of dementia. Bringing together biological, cognitive and clinical information, this book will be an essential reference for clinicians and neuroscientists. It serves as an authoritative and up-to-date overview of the dementias and the prospects for treating them.

Spis treści:
Part I. Biological Perspectives
1. Nonhuman primate models of memory dysfunction in neurodegenerative disease, contributions from comparative neuropsychology Marlene Oscar-Berman, Fiona Bardenhagen
2. Non-primate animal models of motor and cognitive dysfunction associated with Huntingtons Disease Raymond P. Kesner, J. Vincent Filoteo
3. Neuropathology and memory dysfunction in neurodegenerative diseases Julie A. Testa, Roger A. Brumback, Tai-Kyoung Baik, Richard W. Leech, Thomas C. Cannon
4. Neurochemical aspects of memory dysfunction in neurodegenerative disease Edison Miyawaki, William C. Koller
5. Structural neuroimaging correlates of memory dysfunction in neurodegenerative disease Edith V. Sullivan, Deborah A. Cahn, Rosemary Fama, Paula K. Shear
6. Functional neuroimaging correlates of memory dysfunction in neurodegenerative disease Stanley Berent, Bruno Giordani
Summary
7. The biology of neurodegenerative diseases Hans J. Markowitsch
Part II. Cognitive Perspectives
8. The role of executive deficits in memory disorders in neurodegenerative disease Adrian M. Owen, Barbara J. Sahakian, Trevor W. Robbins
9. Prospective memory in aging and neurodegenerative disease Robert G. Knight
10. Remote memory in neurodegenerative disease Robert H. Paul, Joni R. Graber, David C. Bowlby, Julie A. Testa, Michael J. Harnish, William W. Beatty
11. Semantic memory in neurodegenerative disease Joseph W. Fink, Christopher Randolph
12. Non-declarative memory in neurodegenerative disease David P. Salmon, Tara T. Lineweaver, William C. Heindel
Summary
13. Memory in neurodegenerative disease, what has been learnt about the organization of memory? Andrew R. Mayes
Part III. Clinical Perspectives
14. Biological and psychosocial risk factors for dementia and memory loss Diane M. Jacobs, Peter Schofield
15. Cross-cultural issues in the neuropsychological assessment of neurodegenerative disease Andreas U. Monsch, Kirsten I. Taylor, Mark W. Bondi
16. Psychometric issues in the clinical assessment of memory in aging and neurodegenerative disease Anthony M. Paolo
17. The role of memory assessment in the preclinical detection of dementia Mark W. Bondi, Andreas U. Monsch
18. Clinical differentiation of memory disorders in neurodegenerative disease Kathleen A. Welsh-Bohmer, Paula K. Ogrocki
19. The impact of depression on memory in neurodegenerative disease Julie A. Fields, Suzanne Norman, Kristy A. Straits-Tröster, Alexander I. Tröster
20. Preserved cognitive skills in dementia Joni R. Graber, Robert H. Paul, Julie A. Testa, David C. Bowlby, Michael J. Harnish, William W. Beatty
21. Drug treatment of cognitive impairment in neurodegenerative diseases, rationale, current experience, and expectations for the future Louis T. Giron, Jr., William C. Koller
22. Surgical interventions in neurodegenerative disease, impact on memory and cognition Steven B. Wilkinson, Alexander I. Tröster
23. Memory dysfunction in neurodegenerative disease, ethical and legal issues Martin D. Zehr
Summary
24. Memory in neurodegenerative disease, clinical perspectives Thomas Benke.