Transfusion Microbiology

Extensive measures are taken to ensure that blood transfusion poses a minimal microbiological hazard to recipients. Transfusion Microbiology is the definitive text on all aspects of transfusion transmitted infections. This comprehensive text covers all medical, scientific, technical and developmental aspects of this critically important sector of transfusion medicine. A detailed discussion of all infective agents, donor issues, testing and pathogen inactivation is provided. Agents causing major concern recently, such as vCJD, are considered in the context of historical experience with agents such as HIV. All aspects of risk assessment, regulation, cost benefit analysis and quality management are reviewed. Relevant to blood transfusion centres, hospital transfusion laboratories, haematologists and microbiologists, medical, scientific and technical staff, universities and general training programmes worldwide, Transfusion Microbiology provides an up-to-date resource for all practitioners and researchers involved in transfusion medicine.

Spis treści:
Foreword Roger Y. Dodd
Preface
Acknowledgements
Glossary
Introduction John A. Barbara, Roger Eglin
Part I. Agents
1. Hepatitis viruses Denis M. Dwyre and Paul V. Holland
2. Anti-HBc Joan ORiordan
3. Herpes viruses Eleftherios C. Vamvaka and Gary E. Tegtmeier
4. Retroviruses Brian C. Dow, E. W. Fiebig and Michael P. Busch
5. Parvovirus B19 (human erythroviruses) Kevin E. Brown
6. Emerging viruses in transfusion Jean-Pierre Allain
7. Bacterial contamination in blood and blood components Carl P. McDonald and M. A. Blajchman
Annexe, Syphilis Brian C. Dow
8. The protozoan parasites David A. Leiby and Silvano Wendel
9. Prion diseases Marc L. Turner, Patricia E. Hewitt, Moira Bruce and James W. Ironside
Annexe, Testing for prions David Anstee and Gary Mallinson
Part II. Selection and Testing
10. Blood donor selection and qualification Virge James
11. Current serological methods of testing and automation Peter D. Rogan
12. Confirmatory testing and donor readmission Alan D. Kitchen and Brian C. Dow
13. The strategy for applications of nucleic acid testing Paul R. Grant and Richard S. Tedder
14. Nucleic acid testing, general view W. Kurt Roth
15. Nucleic acid testing, the US approach Susan L. Stramer
16. Nucleic acid testing, the English approach Roger Eglin
17. Quality in the screening of donations for transfusion transmissible infections Alan D. Kitchen and John A. Barbara
18. Microbiological blood testing and new technologies Juraj Petrik
19. Processing and components, Leucodepletion and pathogen reduction Rebecca Cardigan, Chris Prowse and Lorna M. Williamson
20. Fractionated products Peter R. Foster and Carol Bienek
Part III. Surveillance, Risk and Regulation
21. Serious hazards of transfusion (SHOT), Haemovigilance Elizabeth M. Love
22. Investigation of post transfusion infection Patricia E. Hewitt and Chris Moore
23. Notification of donors with significant microbiological test results Patricia E. Hewitt and Chris Moore
24. Researching the natural history of transfusion transmitted infections, the UK hepatitis C national register Helen Harris
25. How to assess risk, prospective studies and calculations Kate Soldan and Katy Davison
26. Risk management Arturo Pereira
27. The regulatory environment in Europe Virge James
28. Blood safety in developing countries Jean-Pierre Allain, Elizabeth Vinelli and Yasmin Ayob
Index.