Cytokine Regulation of Humoral Immunity: Basic and Clinical Aspects

Basic and clinical scientists with an interest in how cytokines regulate the production of antibody, and the selective expression of distinct antibody classes in response to microbial and other antigenic challenges, now have a single, comprehensive and timely volume covering this complex field. Cytokine Regulation of Humoral Immunity: Basic and Clinical Aspects uniquely focuses on the impact of the cytokine network on the humoral immune response, as well as its implications for the evolving field of cytokine–based medical therapeutics. With introductory chapters on basic B lymphocyte biology, a systematic and detailed review of the major B cell active cytokines,and discussions on cytokine regulation of normal and pathogenic humoral immune states, this highly referenced book will serve as a valuable source of information for both students and seasoned investigators active in multiple branches of basic and clinical immunology.

Spis treści:
Partial table of contents:
GENERAL CONCEPTS.
B–Cell Subpopulations and Microenvironments (T. Waldschmidt).
Immunoglobulin Class Switching (M. Lorenz & A. Radbruch).
CYTOKINES.
Interleukin–2 (M. McIlraith & P. Lipsky).
Interleukin–5 (K. Takatsu).
Interferon–Gamma (C. Snapper).
Neuropeptides (H. Kimata).
PATHOPHYSIOLOGY.
IgE Regulation in Allergy and Helminth Parasite Infections (R. Coffman).
Regulation of Mucosal Immunity (K. Beagley, et al.).
Index.

Okładka tylna:
Basic and clinical scientists with an interest in how cytokines regulate the production of antibody, and the selective expression of distinct antibody classes in response to microbial and other antigenic challenges, now have a single, comprehensive and timely volume covering this complex field. Cytokine Regulation of Humoral Immunity: Basic and Clinical Aspects uniquely focuses on the impact of the cytokine network on the humoral immune response, as well a s its implications for the evolving field of cytokine–based medical therapeutics. With introductory chapters on basic B lymphocyte biology, a systematic and detailed review of the major B cell active cytokines,and discussions on cytokine regulation of normal and pathogenic humoral immune states, this highly referenced book will serve as a valuable source of information for both students and seasoned investigators active in multiple branches of basic and clinical immunology.