Advanced Immunochemistry

This comprehensive treatment of immunochemistry theory offers the kind of information essential to furthering the biotechnological development of advances in molecular and cellular immunology. More than just a review of the principles, the Second Edition of Advanced Immunochemistry presents a full exposition of modern immunochemical theory and knowledge. Incorporating the major developments in immunochemistry over the past two decades, this exciting text presents the latest information on the progress in such areas as: immunoglobulin structures; applications of molecular genetics to the understanding of immunoglobulin genes and supergene families; molecular and cellular bases of antibody diversity; antibody binding to specific epitopes of antigen molecules; and idiotypy. This Second Edition will serve as a comprehensive reference to the structure and function of immunoglobulins and as a basis for understanding the complexities of immune responses.

Spis treści:
STRUCTURE OF ANTIBODIES.
The Light Chains of the Immunoglobulins.
The Heavy Chains of the Immunoglobulins.
The Secondary, Tertiary, and Quaternary Structures of Assembled Immunoglobulins.
The Antibody Bonding Site.
Effector Functions of Immunoglobulins.
REACTIONS OF ANTIBODIES.
Specificity and Complementarity.
Affinity.
The Drive Towards Homogeneity and the Advent of Monoclonal Antibodies.
Immune Complexes.
The Immunochemistry of Viruses.
The Immunochemistry of Some Non–Viral Multiepitopic Antigens.
Immune Responses and Their Regulation.