Mineralized Tissues in Oral and Craniofacial Science: Biological Principles and Clinical Correlates

Mineralized Tissues in Oral and Craniofacial Science is amajor comprehensive update on knowledge in the field of mineralizedtissues in the oral and craniofacial region. Drs. McCauley andSomerman assembled an international team of researchers andclinicians, offering a global perspective on the current knowledgein this field. Basic and clinical correlates reinforce thesignificance of research to clinical diagnoses and therapies,written in a manner that lends easily to their use for case studyteaching venues.

Section 1 features the many aspects of bone in the craniofacialregion, including embryology, cell biology, and stem cell biology.Section 2 focuses on teeth–tooth development, dentin, enamel,cementum, and tooth regeneration. Section 3 discusses theinteraction between bones and teeth, including those associatedwith inflammatory processes, periodontal ligaments, biomechanics,and other impact factors–such as nutrition, metabolic bone diseasesand therapeutic modalities.

The novel approach of linking the basic principles of the cell andmolecular biology of hard tissues to clinical correlates willappeal to readers at all levels of their research careers, bothstudents and faculty; faculty interested in a comprehensive textfor reference; and  clinicians interested in the biologicaspects of bones and teeth.

Contributors vii

Preface xv

Acknowledgments xvii

Foreword xix

Section 1 Bones of the oral–dental and craniofacial complex1

1 Embryology of craniofacial bones 3
Antonio Nanci and Pierre Moffatt

2 Clinical correlate: cleft lip and palate 13
Emily R. Gallagher and Joel Berg

3 Cell and molecular biology of the osteoclast and boneresorption 17
Martin Biosse–Duplan, William C. Horne, and Roland Baron

4 Clinical correlate: osteopetrosis 29
Paul C. Edwards and Nasser Said–Al–Naief

5 Clinical correlate: CLCN7–associated autosomal recessiveosteopetrosis 35
Piranit Nik Kantaputra

6 Osteoblasts of craniofacial bone 43
Renny T. Franceschi, Chunxi Ge, and Christopher G.Wilson

7 Clinical correlate: cleidocranial dysplasia 59
Shu Takeda, Nobuhiko Haga, and Keiji Moriyama

8 Cell biology of craniofacial bone: osteocytes 63
Lynda F. Bonewald

9 Clinical correlate: Van Buchem disease 71
H.–J. Prins, A.L.J.J. Bronckers, and J. Klein–Nulend

10 Stem cell biology in the craniofacial apparatus 79
Carolina Parada, Kentaro Akiyama, Yang Chai, and SongtaoShi

11 Clinical correlate: stem cell therapy for craniofacial boneregeneration 93
Giorgio Pagni, William V. Giannobile, and DarnellKaigler

12 Extracellular matrix and mineralization of craniofacial bone99
Marc D. McKee, Monzur Murshed, and Mari T. Kaartinen

13 Clinical correlate: osteogenesis imperfecta 111
Peter H. Byers

Section 2 Teeth 117

14 Tooth development 119
Irma Thesleff and Emma Juuri

15 Clinical correlate: tooth agenesis 129
Rena N. D Souza and Gabriele I. Mues

16 Dentin 135
Chunlin Qin and Jian Q. Feng

17 Clinical correlate: dentinogenesis imperfecta, restorativeprocedures, and caries 143Yong–Hee Patricia Chun and Jan CC.Hu

18 Enamel fabrication: the story of amelogenesis 153
Carolyn W. Gibson and Malcolm L. Snead

19 Clinical correlate: amelogenesis imperfecta 163
Rochelle G. Lindemeyer

20 Cementum 169
Brian L. Foster and Martha J. Somerman

21 Clinical correlate: case study of identical twins withcementum and periodontal defects resulting fromodontohypophosphatasia 183
Thaisângela L. Rodrigues, Ana Paula Georgetti, LucianeMartins, João S. Pereira Neto, Brian L. Foster, and FranciscoH. Nociti Jr.

22 Dental engineering: tooth regeneration 191
Weibo Zhang and Pamela C. Yelick

23 Clinical correlate: periodontal regeneration 201
Jia–Hui Fu and Hom–Lay Wang

24 Clinical correlate: natural tooth regeneration 207
Gary E. Heyamoto

25 Clinical correlate: regenerative endodontics in an immaturetooth with pulpal necrosis and
periapical pathosis 211
Tatiana M. Botero, Christine M. Sedgley, Martha I. Paniagua, andDiego M. Tobón

Section 3 Bones and teeth 217

26 Bone and tooth interface: periodontal ligament 219
P. Mark Bartold

27 Clinical correlate: two cases of destructive periodontaldisease 231
Rahime Meral Nohutcu

28 Periodontal disease and infl ammationinduced bone remodeling237
Dana T. Graves, Elliot D. Rosenstein, Carlos Rossa Jr., andJoseph P. Fiorellini

29 Clinical correlate: endodontic lesions 249
Matthew DiAndreth and Hongjiao Ouyang

30 Biomechanics of teeth in bone: function, movement, andprosthetic rehabilitation 255
Susan W. Herring

31 Clinical correlate: biomechanics of teeth in bone 269
Gregory King, Geoffrey Greenlee, Paola Leone, and GregoryVaughn

32 Impact of metabolic bone disease on craniofacial bones andteeth 277
Jill Bashutski, L. Susan Taichman, and Laurie K.McCauley

33 Clinical correlate: renal osteodystrophy 291
Flavia Pirih, Gabriella Tehrany, and Tara Aghaloo

34 Mineral metabolism and its impact on craniofacial bones andteeth 297
Jian Q. Feng and Chunlin Qin

35 Clinical correlate: mineral metabolism and disruption ofdentoalveolar development in a case of craniometaphyseal dysplasia(CMD) 305
Hai Zhang and Brian Foster

36 Sun, nutrition, and the mineralization of bones and teeth311
Philippe P. Hujoel

37 Clinical correlate: vitamin D deficiency 327
Ana Lucia Seminario and Elizabeth Velan

38 Impact of therapeutic modalities on craniofacial bones andteeth 331
Purnima S. Kumar and Angelo Mariotti

39 Clinical correlate: osteoradionecrosis of the jaws (ORN)343
Nicholas M. Makhoul and Brent B. Ward

Index 349

Figures from the book are available for download atwww.wiley.com/go/mccauley

Laurie K. McCauley, DDS, PhD is the William K. and Mary Anne Najjar Professor and Chair of the Department of Periodontics and Oral Medicine, and Professor in the Department of Pathology at the University of Michigan in Ann Arbor, Michigan.

Martha J. Somerman, DDS, PhD, formerly Dean and Professor, University of Washington School of Dentistry, is currently the Director of the National Institute of Dental and Craniofacial Research, and Chief, Laboratory for Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases at the National Institutes of Health in Bethesda, Maryland.

Notwithstanding these minor points, the book is very wellstructured and provides a comprehensive overview of all themineralized tissues in in the craniofacial complex, withinteresting aspects of the requirements for successful clinicalapplications.   (Implant Dentistry, 1 June2013)

In summary , this book is commendable  for theextent of its content and its ability to remain up to date.  It serves the needs not only of first–year students , butalso of various specialists in training and all practitionerslooking for a rationale in their diagnosis andtreatment.   (British Dental Journal, 8 December2012)