Introduction to Neural Engineering for Motor Rehabilitation

Neural engineering is a discipline that uses engineering techniques to understand, repair, replace, enhance, or treat diseases of neural systems. Currently, no book other than this one covers this broad range of topics within motor rehabilitation technology. With a focus on cutting edge technology, it describes state–of–the–art methods within this field, from brain–computer interfaces to spinal and cortical plasticity. Touching on electrode design, signal processing, the neurophysiology of movement, robotics, and much more, this innovative volume collects the latest information for a wide range of readers working in biomedical engineering.

CONTRIBUTORS ix PREFACE xv PART I INJURIES OF THE NERVOUS SYSTEM 1 1 Diseases and Injuries of the Central Nervous System Leading to Sensory–Motor Impairment 3 Dejan B. Popoviæ and Thomas Sinkjær 2 Peripheral and Spinal Plasticity after Nerve Injuries 21 Xavier Navarro 3 Motor Control Modules of Human Movement in Health and Disease 39 Yuri P. Ivanenko, Germana Cappellini, Marco Molinari, and Francesco Lacquaniti PART II SIGNAL DETECTION AND CONDITIONING 61 4 Progress in Peripheral Neural Interfaces 63 Shaoyu Qiao, Kevin A. Mauser, and Ken Yoshida 5 Multimodal, Multisite Neuronal Recordings for Brain Research 95 Ulrich G. Hofmann, Peter Detemple, and Yijing Xie 6 Surface Electromyogram Detection 113 Alberto Botter, Marco Gazzoni, and Roberto Merletti 7 Methods for Noninvasive Electroencephalogram Detection 137 Christoph Guger and Günter Edlinger 8 Spike Sorting 155 Di Ge and Dario Farina 9 Wavelet Denoising and Conditioning of Neural Recordings 173 Luca Citi and Silvestro Micera 10 Instantaneous Cross–Correlation Analysis of Neural Ensembles with High Temporal Resolution 183 António R.C. Paiva, Il Park, José C. Príncipe, and Justin C. Sanchez 11 Unsupervised Decomposition Methods for Analysis of Multimodal Neural Data 199 Felix Biessmann, Frank C. Meinecke, and Klaus–Robert Müller PART III FUNCTION REPLACEMENT (PROSTHESES AND ORTHOSIS) 235 12 Brain–Computer Interfaces 237 José del R. Millán 13 Movement–Related Cortical Potentials and Their Application in Brain–Computer Interfacing 253 Kim Dremstrup, Ying Gu, Omar Feix do Nascimento, and Dario Farina 14 Introduction to Upper Limb Prosthetics 267 Bernhard Graimann and Hans Dietl 15 Myoelectric Prostheses and Targeted Reinnervation 291 Levi Hargrove, Erik Scheme, and Kevin Englehart 16 Controlling Prostheses Using PNS Invasive Interfaces for Amputees 311 Jacopo Carpaneto, Luca Citi, Stanisa Raspopovic, Jacopo Rigosa, and Silvestro Micera 17 Exoskeletal Robotics for Functional Substitution 327 José Luis Pons, Juan C. Moreno, and Eduardo Rocon PART IV FUNCTION RESTORATION 349 18 Methods for Movement Restoration 351 Dejan B. Popoviæ, and Mirjana B. Popoviæ 19 Advanced User Interfaces for Upper Limb Functional Electrical Stimulation 377 Elaine A. Corbett, Christian Ethier, Emily R. Oby, Konrad Kording, Eric J. Perreault, and Lee E. Miller 20 Customized Modeling and Simulations for the Control of FES–Assisted Walking of Individuals with Hemiplegia 401 Strahinja Došen and Dejan B. Popoviæ 21 ActiGait®: A Partly Implantable Drop–Foot Stimulator System 421 Birgit Larsen and Andrei Patriciu 22 Selectivity of Peripheral Neural Interfaces 433 Winnie Jensen and Kristian Rauhe Harreby PART V REHABILITATION THROUGH NEUROMODULATION 461 23 Brain–Computer Interface Applied to Motor Recovery after Brain Injury 463 Janis J. Daly 24 Functional Electrical Therapy of Upper Extremities 477 Mirjana B. Popoviæ and Dejan B. Popoviæ 25 Gait Rehabilitation Using Nociceptive Withdrawal Refl ex–Based Functional Electrical Therapy in Stroke Patients 493 Ole K. Andersen and Erika G. Spaich 26 Robot–Assisted Neurorehabilitation 505 Vittorio Sanguineti, Maura Casadio, Lorenzo Masia, Valentina Squeri, and Pietro G. Morasso 27 Paired Associative Stimulation 529 Natalie Mrachacz–Kersting 28 Operant Conditioning of Spinal Refl exes for Motor Rehabilitation after CNS Damage 549 Aiko K. Thompson and Jonathan R. Wolpaw INDEX 571