Principles of Toxicology: Environmental and Industrial Applications

A fully updated and expanded edition of the bestselling guide on toxicology and its practical application Since the publication of the second edition the field of toxicology and continued changing expanding.  Principles of Toxicology: Environmental and Industrial Applications, Third Edition continues to present compactly and efficiently the scientific basis to toxicology as it applies to the workplace and the environment. The book covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. Through contributions from leading experts in diverse fields, Principles of Toxicology, Third Edition features: • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms The new edition also covers emerging areas of toxicology and presents more information on applications of toxicology.  New topics include: Toxicokinetics; Omics Technologies; Developmental Toxicity; Nanotoxicology; Computational Toxicology; and  Determination of Causation in Toxicology

Preface 1. General Principles of Toxicology Robert C. James, Stephen M. Roberts, and Phillip L. Williams 2. Absorption, Distribution, Biotransformation, and Elimination of Toxic Agents Michael R. Franklin 3. Toxicokinetics Rebecca A. Clewell and Harvey J. Clewell III 4. Omics Technologies in Toxicology Mary Jane Cunningham 5. Hematotoxicity: Toxic Effects on the Blood Sherilyn A. Gross 6. Hepatotoxicity: Toxic Effects on the Liver Robert C. James and Stephen M. Roberts 7. Nephrotoxicity: Toxic Effects on the Kidney Lawrence H. Lash 8. Neurotoxicity: Toxic Effects on the Nervous System William M. Caudle and Gary W. Miller 9. Dermatotoxicity: Toxic Effects on the Skin Sailesh Konda and Howard J. Maibach Dermal Toxiclogy 10. Pulmonotoxicity: Toxic Effects on the Lung Cuiqing Liu and Qinghua Sun 11. Immunotoxicity: Toxic Effects on the Immune System Eric S. Sobel and Stephen M. Roberts 12. Toxic Effects on Reproduction Mary Hixon 13. Developmental Toxicity Vincent F. Garry and Peter Truran 14. Mutagenesis and Genetic Toxicology Martha M. Moore, Meagan B. Myers, and Robert H. Heflich 15. Chemical Carcinogenesis James E. Klaunig 16. Properties and Effects of Metals David B. Mayfield, Ari S. Lewis, Lisa A. Bailey, and Barbara D. Beck 17. Properties and Effects of Pesticides Janice Britt 18. Properties and Effects of Solvents Christopher M. Teaf, Michele M. Garber, and J. Michael Kuperberg 19. Nanotoxicology Hongbo Ma, Steven Diamond, Georgia Hinkley, and Stephen M. Roberts 20. Computational Toxicology Richard S. Judson, David M. Reif, and Keith A. Houck 21. Epidemiological Issues in Occupational and Environmental Health Michael S. Bloom and John E. Vena 22. Occupational and Environmental Health Brenda Buikema, T. Renee Anthony, and Fredric Gerr 23. Human Health Risk Assessment Leah D. Stuchal, Robert C. James, and Stephen M. Roberts

Stephen M. Roberts, PhD, is Professor and Program Director of the Center for Environmental and Human Toxicology at the University of Florida, Gainesville Robert C. James, PhD, is Senior Principal Scientisst, ToxStrategies, Inc., Tallahassee, Florida, and Associate Scientist at the Center for Environmental and Human Toxicology at the University of Florida, Gainesville Phillip L. Williams, PhD, is Dean & Georgia Power Professor at the University of Georgia, Athens