Multidimensional NMR Methods for the Solution State

Multidimensional NMR methods have transformed the way in which solution state NMR is used to elucidate the structures of chemical and biochemical systems. The first book covering new developments in nearly a decade, this much–needed resource explains recent experimental methods for the rapid measurement of multidimensional solution–state NMR spectra. With articles written by key developers of the techniques, the coverage deals with both the theoretical tools and the latest practical applications, giving an unmatched guide to students, researchers, technicians, and anyone else working with NMR techniques today.

Spis treści:
Contributors.
Series Preface.
Volume Preface.
Part A: Principles.
1 Multidimensional NMR: an Introduction (Gareth A. Morris, James W. Emsley).
2 Multidimensional Spectroscopy: Concepts (Richard R. Ernst).
3 Ultrafast Multidimensional NMR: Principles and Practice of Single–Scan Methods (Maayan Gal, Lucio Frydman).
4 Fast Multidimensional NMR by Hadamard Spectroscopy (Ray Freeman, Eriks Kupce).
5 Multidimensional NMR by Projection–Reconstruction (Ray Freeman, Eriks Kupce).
6 Rapid Multidimensional NMR: Decomposition Methods and their Applications (Martin Billeter, Doroteya K. Staykova).
7 Multidimensional Correlation Spectroscopy by Covariance NMR (David A. Snyder, Rafael Bruschweiler).
8 Maximum Entropy Methods in Multidimensional NMR (Jeffrey C. Hoch, Mehdi Mobli).
9 Filter Diagonalization Methods for Time–Domain Signals (A. J. Shaka, Vladimir A. Mandelshtam).
10 Fourier Transform and Linear Prediction Methods (Jens J. Led, Henrik Gesmar).
Part B: Techniques.
11 Two–Dimensional J–Resolved Spectroscopy (Gareth A. Morris).
12 COSY (David M. Doddrell).
13 COSY: Quantitative Analysis (Alex D. Bain).
14 E.COSY: Determination of Coupling Constants (Harald Schwalbe, P. Schmidt, Christian Griesinger).
15 Relayed Coherence Transfer Experiments (Philip H. Bolton).
16 TOCSY (Timothy D. W. Claridge).
17 Multiple Quantum Spectroscopy of Liquid Samples (Timothy J. Norwood).
18 NOESY (Michael P. Williamson).
19 ROESY (Ad Bax, Stephan Grzesiek).
20 TOCSY in ROESY and ROESY in TOCSY (J. Schleucher, J. Quant, S. J. Glaser, Christian Griesinger).
21 2D Methods of Monitoring Exchange (Keith G. Orrell).
22 Heteronuclear Shift Correlation Spectroscopy (Thomas T. Nakashima, R. E. D. McClung).
23 2D Methods for the Measurement of Long–Range Proton–Carbon Coupling Constants (Teodor Parella).
24 Homonuclear 3D NMR of Biomolecules Rolf Boelens, Robert Kaptein).
25 3D HMQC–NOESY, NOESY–HMQC, and NOESY–HSQC (Ranjith Muhandiram, Lewis E. Kay).
26 3D and 4D Heteronuclear Magnetic Resonance (G. Marius Clore, Angela M. Gronenborn).
Part C: Applications.
27 2D Carbon–Heteroelement Correlation (Stefan Berger).
28 Multidimensional NMR in Organotin Chemistry and Catalysis (Monique Biesemans, Rudolph Willem).
29 2D NMR of Molecules Oriented in Liquid Crystalline Phases (Anil Kumar).
30 2D NMR of Molecules Oriented in Liquid Crystals—Recent Developments (Anil Kumar, N. Suryaprakash).
31 Local Field Experiments in Liquid Crystals (Stefano Caldarelli).
32 Multiple Quantum Spectroscopy in Liquid Crystalline Solvents (Leslie D. Field).
33 Biological Macromolecules: Structure Determination in Solution (Kurt W¨uthrich).
34 Structures of Larger Proteins, Protein–Ligand, and Protein–DNA Complexes by Multidimensional Heteronuclear NMR (G. Marius Clore, Angela M. Gronenborn).
35 Rapid Multidimensional NMR: Fast Pulsing Techniques and their A pplications to Proteins (Bernhard Brutscher, Paul Schanda).
Part D: Related Techniques.
36 Diffusion–Ordered Spectroscopy (Gareth A. Morris).
37 2D Relaxometry (Brian P. Hills).
Index.