Label–Free Technologies For Drug Discovery

Over the past two decades the benefits of label–free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories.
 
Label–Free Technologies For Drug Discovery summarises the latest and emerging developments in label–free detection systems, their underlying technology principles and end–user case studies that reveal the power and limitations of label–free in all areas of drug discovery.
 
Key focus areas include the use of label–free technologies in:
 screening technologies high–content technologies hit finding and hit validation strategies mode of action and ADME/T access to difficult target classes cell–based receptor/ligand interactions particularly orphan receptors non–invasive cell proliferation and in vitro cytotoxicity testing antibody and small molecule affinity and kinetic analysis
 
Label–Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high–throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.