Fundamentals of Heterocyclic Chemistry: Importance in Nature and in the Synthesis of Pharmaceuticals

Heterocyclic chemistry is of prime importance as a sub–discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularlyIntroduces students to heterocyclic chemistry and synthesis with practical examples of applied methodologyEmphasizes natural product and pharmaceutical applicationsProvides graduate students and researchers in the pharmaceutical and related sciences with a background in the fieldIncludes problem sets with several chapters

Spis treści:
Preface. For Whom this Book is Written.
Chapter 1. The Scope of the Field of Heterocyclic Chemistry.
Chapter 2. Common Ring Systems and the Naming of Heterocyclic Compounds.
Chapter 3. Nature as a Source of Heterocyclic Compounds.
Chapter 4. Principles of Synthesis of Aromatic Rings by Intramolecular Cyclization.
Chapter 5. Synthesis of Heterocyclic Systems by Cycloaddition Reactions.
Chapter 6. Aromaticity and Other Special Properties of Heterocycles: Pi–Deficient Ring Systems.
Chapter 7. Aromaticity and Other Special Properties of Heterocycles: Pi–Excessive Ring Systems; Mesoionic Ring Systems.
Chapter 8. The Importance of Heterocycles in Medicine.
Chapter 9. Synthetic Methods for Some Prominent Heterocyclic Families, Illustrated with Examples of Pharmaceuticals Synthesis.
Chapter 10. Geometric and Stereochemical Aspects of Non–Aromatic Heterocyclic Rings.
Chapter 11. Synthetic Heterocyclic Compounds in Agricultural and Other Applications.
Appendix I. Unified Aromaticity Indices (IA) of Bird.
Appendix II. Solutions to Review Exercises.