Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management, and Testing

This book presents strategies to reduce drug and chemical residues in food from livestock production, and also some of the newer technologies and theories that will shape drug residues management in the future. One of the novel features of this book is that it ties in the realities of veterinary clinical practice and use of these drugs in food animals with regulatory standards and mitigation practices. Highlighting approaches from around the world, the book details strategies to minimize contamination, residue monitoring programs, and classes of drugs and chemicals that pose contaminant risk in livestock. The first section focuses on strategies that are part of public policy in national and international agencies and how these agencies assess the toxicology of veterinary drugs and contaminants. These chapters provide a general introduction to basic pharmacokinetic principles pertaining to estimating a safe withdrawal time for veterinary drugs and contaminants. The second half focuses on the use of major drug classes in livestock food animal production systems and those drugs most likely targeted for regulatory policy, pharmacokinetic modelling, and chemical residue monitoring.

Ronald Baynes is a Professor of Pharmacology and Director of the Center of Chemical Toxicology Research and Pharmacokinetics at the College of Veterinary Medicine at North Carolina State University and Fellow, American Academy of Veterinary Pharmacology and Therapeutics He has consulted for the National Institute of Environmental Health Sciences, the US Environmental and Protection Agency, and National Institute of Occupational Safety and Health on chemical exposure–related topics. Jim Riviere  is The MacDonald Chair in Veterinary Medicine and University Distinguished Professor at Kansas State University. He is an elected member of the Institute of Medicine of the National Academies, serves on its Food and Nutrition Board, and is a fellow of the Academy of Toxicological Sciences.