Molecularly Imprinted Polymers: Man-Made Mimics of Antibodies and their Application in Analytical Chemistry

This book is divided into 5 sections starting with an historic perspective and fundamental aspects on the synthesis and recognition by imprinted polymers. The second section contains 8 up-to-date overview chapters on current approaches to molecular and ion imprinting. This is followed by two chapters on new material morphologies and in the last two sections various analytical applications of imprinted polymers are given, with the last four chapters devoted to the promising field of imprinted polymers in chemical sensors.
The authors of this volume have widely different backgrounds; mainly polymer chemistry, organic chemistry, biochemistry and analytical chemistry, which means that this book has an interdisciplinary character and should appeal to a broad audience.

Chapter Headings. An Historical Perspective of the Development of Molecular Imprinting. Fundamental Aspects on the Synthesis and Characterisation of Imprinted Network Polymers. Thermodynamic Principles Underlying Molecularly Imprinted Formulation and Ligand Recognition. Molecular Imprinting with Covalent or Stoichiometric Non-Covalent Interactions. The Non-Covalent Approach to Molecular Imprinting. Metal-Ion Coordination in Designing Molecularly Imprinted Polymeric Receptors. Covalent Imprinting using Sacrificial Spacers. Molecular Imprinting - Approaches using Inorganic Matrices. Imprinting Polymerisation for Recognition and Separation of Metal Ions. Bio-Imprinting: Polymeric Receptors with and for Biological Macromolecules. Surface Imprinting of Microorganisms. Polymerisation for the Formation of Imprinted Beads. Techniques for the In Situ Preparation of Imprinted Polymers. Application of Molecularly Imprinted Polymers in Competitive Ligand Binding Assays for Analysis of Biological Samples. Molecularly Imprinted Polymers in Solid Phase Extractions. Capillary Electrochromatography Based on Molecular Imprinting. Molecularly Imprinted in Enantiomer Separations. Biomimetic Electrochemical Sensors Based on Molecular Imprinting. Ionic Sensors Based on Molecularly Imprinted Polymers. Toward Optical Sensors for Biologically Active Molecules. Non-Covalent Molecularly Imprinted Sensors for Vapours, Polyaromatic Hydrocarbons and Complex Mixtures.