Neurology and Pregnancy: Pathophysiology and Patient Care

Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health.

Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections.

Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.

Discusses neuroendocrine, brain, PNS, and cerebro-vascular changes in pregnancyIncludes neurological care of the pregnant patientCovers neuroimaging and monitoring techniquesReviews common neurological complications with pregnancySupplies illustrative case study examples

SECTION I. Neurophysiologic changes in pregnancy 1. Neuroendocrine mechanisms of reproduction 2. Neurophysiological and cognitive changes in pregnancy 3. Adaptations in autonomic nervous system regulation in normal and hypertensive pregnancy 4. Physiology of the cerebrovascular adaptation to pregnancy 5. Neurobiology of maternal mental illness

SECTION II. The pregnant patient: General issues in neurologic care 6. Epidemiology of neurologic disease in pregnancy 7. Neuro-obstetrics: A multidisciplinary approach to care of women with neurologic disease 8. Perinatal pharmacology and safety profiles 9. Neuroimaging and radiation exposure in pregnancy 10. Neuro-anesthesiology in pregnancy 11. Neurocritical care of the pregnant patient 12. Neurologic complications of medical conditions in pregnancy 13. The ethics of neurologically complicated pregnancies

SECTION III. Prenatal neurologic diagnoses: pathophysiology, diagnosis, and management 14. The developing brain by trimester 15. Diagnosis and management of congenital neurologic disease during pregnancy 16. Perinatal stroke