The Cerebellum: From Embryology to Diagnostic Investigations: Handbook of Clinical Neurology Series

The Cerebellum: From Embryology to Diagnostic Investigations is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. This volume is organized into the following sections: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: neuroimaging including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum to adult cerebellum) encountered during daily practice, and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders).

Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases, allowing for better management of affected children and adults, in the quest to improve their quality of lifeExplores long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseasesFeatures chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases

Section I. Introduction 1. Historical view

Section II. Embryology, Anatomy and Function 2. Embryology 3. Principles of organization of the human cerebellum: macro and microanatomy 4. Functional topography of the human cerebellum 5. Topography of the cerebellum in relationship to social brain regions and emotions 6. Physiology of the cerebellum 7. Cerebellar networks and neuropathology of cerebellar developmental disorders 8. The neuropathology of the adult cerebellum 9. Cerebellar motor syndrome from children to the elderly 10. Cognitive aspects: sequencing, behavior and executive functions 11. Language and the cerebellum

Section III. Diagnostic Investigations 12. Ultrasound and CT of the posterior fossa in neonates 13. Conventional MRI 14. Probing the neuroanatomy of the cerebellum using tractography 15. Nuclear medicine of the cerebellum 16. Genetics of cerebellar disorders 17. Laboratory investigations 18. Neurophysiology of gait 19. Neuro-ophthalmologic assessment and investigations in children and adults with cerebellar diseases 20. Scales for the clinical evaluation of cerebellar disorders