Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease.

Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics.

Brings the reader up-to-date and allows easy access to individual topics in one placeWritten by a respected panel of distinguished physicians/scientists actively involved in the field of Antiphospholipid SyndromeIncludes box summaries at the end of each chapter that highlight important topicsGives up-to-date, basic knowledge and a modern approach to diagnosis and therapyProvides a comprehensive review of this major diseaseIncludes information on treatment options available

1. History, Classification, and Subsets of the Antiphospholipid Syndrome 2. Epidemiology of the Antiphospholipid Syndrome 3. Mechanisms of Action of the Antiphospholipid Antibodies 4. Laboratory Markers With Clinical Significance in the Antiphospholipid Syndrome 5. Genetic and Epigenetic Aspects of Antiphospholipid Syndrome: What we knew, what we know 6. Thrombotic Manifestations of the Antiphospholipid Syndrome 7. Obstetric Manifestations of the Antiphospholipid Syndrome 8. Thrombocytopenia in the Antiphospholipid Syndrome 9. Nonclassification Criteria Manifestations of the Antiphospholipid Syndrome 10. Paediatric Antiphospholipid Syndrome 11. Antiphospholipid Antibodies and Their Relationship With Infections, Vaccines, and Drugs 12. Antiphospholipid Syndrome Associated With Malignancies 13. Antiphospholipid Antibodies and Atherosclerosis 14. Global Antiphospholipid Syndrome Score 15. Primary Prophylaxis in Patients With Positive Antiphospholipid Antibodies 16. Treatment of Thrombosis in Antiphospholipid Syndrome 17. Treatment of Catastrophic Antiphospholipid Syndrome 18. Treatment of Pregnancy Complications in Antiphospholipid Syndrome 19. Prognosis in Antiphospholipid Syndrome