Arteriovenous and Cavernous Malformations

Arteriovenous and Cavernous Malformations, Volume 143, is the latest addition in the ongoing HCN series, an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of AVMs, while also providing expert clinical information on the management and treatment of these lesions.

In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad, yet objective, review of this pathology, with updates from the latest scientific literature and data supporting current practices.

Offers an evidence-based focus with coverage of both the scientific and clinical aspects of cavernous malformationsAddresses epidemiology, etiology, diagnosis, and geneticsContains clinical insights regarding indications for surgery, surgical techniques, outcomes, and prognostic factors drawn from the authors' extensive experiencesEdited work with chapters authored by leaders in the field from around the globe – the broadest, most expert coverage available

PART I. ARTERIOVENOUS MALFORMATIONS Section 1. Cerebral Arteriovenous Malformations 1. Epidemiology, genetics, pathophysiology and prognostic classifications of cerebral arteriovenous malformations 2. The natural history of cerebral arteriovenous malformations 3. Arteriovenous malformations: epidemiology, clinical presentation and diagnostic evaluation 4. Seizures Associated with Cerebral Arteriovenous Malformations 5. Surgical Management 6. Endovascular management of arteriovenous malformations 7. Radiosurgery for the management of cerebral arteriovenous malformations 8. Multimodality Management Section 2. Cerebral Dural Arteriovenous Fistulas 9. Epidemiology, clinical presentation, diagnostic evaluation, and prognosis of cerebral dural arteriovenous fistulas 10. Surgical management of cerebral dural arteriovenous fistulae 11. Endovascular Management 12. Radiation Management Section 3. Spinal Vascular Malformations 13. Classification and pathophysiology of spinal vascular malformations 14. Epidemiology, Clinical Presentation, Diagnostic Evaluation and Prognosis 15. Spinal Arteriovenous Malformations: surgical management 16. Endovascular treatment of spinal arteriovenous malformations 17. Spinal Arteriovenous Malformations: radiation management 18. Spinal Arteriovenous Fistulas: surgical management 19. Spinal Arteriovenous Fistulas: endovascular management 20. Spinal subarachnoid hemorrhage and aneurysms Section 4. Animal models 21. Animal models of arteriovenous malformation PART II. CAVERNOUS MALFORMATIONS 22 Natural History of Cerebral Cavernous Malformations 23 Natural History of Spinal Cavernous Malformations 24 Genetics of Cavernous Malformations 25 Epidemiology of Cavernous Malformations 26 Radiology and Imaging for Cavernous Malformations 27 Pathology of Cavernous Malformations 28 Developmental Venous Anomalies 29 Supratentorial Cavernous Malformations 30 Brainstem and Cerebellar Cavernous Malformations 31 Thalamic Cavernous Malformations 32 Spinal Cavernous Malformations 34 Pharmacotherapy for Cavernous Malformations