Orexin/Hypocretin System

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist.

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

1. Many Faces of Orexin/Hypocretin

Anantha Shekhar

2. Overview of Orexin/Hypocretin System

Michihiro Mieda and Takeshi Sakurai

3. Hypocretins and the Neurobiology of Sleep-Wake Mechanisms

Luis de Lecea

4. Respiration and Autonomic Regulation and Orexin

Eugene Nattie and Aihua Li

5. Orexins, Feeding and Energy Balance

Elodie Girault, Chun-Xia Yi, Eric Fliers and Andries Kalsbeek

6. Orexin and Natural Reward: Feeding, Maternal and Male Sexual Behavior

Andrea R. Di Sebastiano and Lique M. Coolen

7. Multiple Roles for Orexin/Hypocretin in Addiction

Stephen V. Mahler, Rachel J. Smith, David E. Moorman, Gregory S. Sartor and Gary Aston-Jones

8. Hypocretin Modulation of Drug-Induced Synaptic Plasticity

Corey Baimel and Stephanie L. Borgland

9. Orexin, Stress and Anxiety/Panic States

Philip L. Johnson Andrei Molosh, Stephanie D. Fitz, William A. Truitt and Anantha Shekhar

10. Orexin Receptors as Therapeutic Drug Targets Anthony L. Gotter, Anthony J. Roecker, Richard Hargreaves, Paul J. Coleman, Christopher J. Winrow and John J. Renger