Studies in Natural Products Chemistry: Bioactive Natural Products (Part M)

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.

The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions.

* Timely reviews written by international authorities in the field
* Topics ranging from purely chemical to very biological
* The 13th volume in the series to be devoted to bioactive natural products

Foreword
Preface
Contributors
Focus on fluorescent proteins
Structure, function and mode of action of select arthropod neuropeptides
Natural products as modulators of apoptosis and their role in inflammation
Sesquiterpenes classified as phytoalexins
Bioactive triterpenes and related compounds from celastraceae
Structure-activity relationships of sesquiterpene lactones
Synthetic investigations in the field of drimane sesquiterpenoids
Quassinoids: Structure diversity, biological activity and synthetic studies
The diterpenoids from the genus Sideritis
Recent developments in the asymmetric synthesis of lignans
Natural oligostilbenes
Isolation, structure elucidation and bioactivities of phenylethanoid glycosides from Cistanche, Forsythia and Plantago plants
Pharmacological activities of phenylpropanoids glycosides
Development of tubulin inhibitors as antimitotic agents for cancer therapy
Cholesterol biosynthesis inhibitors of microbial origin
Structure-activity relationships of curcumin and its analogs with different
biological activities
The Vinca alkaloids: From biosynthesis and accumulation in plant cells,
to uptake, activity and metabolism in animal cells
The chemistry of Olea Europaea
The chemistry of the genus Cicer L.
New research and development on the Formosan annonaceous plants
Structural and functional aspects of fungal glycosphingolipids
Phytochemical studies and pharmacological activities of plants in genus Hedyotis/Oldeanlandia
Subject Index