Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens.

The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle.

Provides the information users need to integrate antibacterial nanoparticles into future treatmentsGives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection

1. Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon 2. The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR) 3. Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment 4. Metal Nanoparticles for Microbial Infection 5. Lipid-Based Nanopharmaceuticals in Antimicrobial Therapy 6. Organic Polymeric Nanomaterials as Advanced Tools in the Fight Against Antibiotic-Resistant Infections 7. Bacteriocins and Nanotechnology 8. Graphene-Microbial Interactions