UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices

UHMWPE Biomaterials Handbook, Third Edition, describes the science, development, properties, and application of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. UHMWPE is now the material of choice for joint replacements, and is increasingly being used in fibers for sutures. This book is a one-stop reference for information on this advanced material, covering both introductory topics and the most advanced developments.

The third edition adds six new chapters on a range of topics, including the latest in anti-oxidant technologies for stabilizing HXLPE and up-to-date systematic reviews of the clinical literature for HXLPE in hips and knees. The book chronicles the rise and fall of all-metal hip implants, as well as the increased use of ceramic biomaterials and UHMWPE for this application. This book also brings orthopedic researchers and practitioners up to date on the stabilization of UHMWPE with antioxidants, as well as the choices of antioxidant available for practitioners.

The book also thoroughly assesses the clinical performance of HXLPE, as well as alternative bearings in knee replacement and UHMWPE articulations with polyether ether ketone (PEEK).

Written and edited by the top experts in the field of UHMWPE, this is the only state-of-the-art reference for professionals, researchers, and clinicians working with this material.

The only complete reference for professionals, researchers, and clinicians working with ultra-high molecular weight polyethylene biomaterials technologies for joint replacement and implantsNew edition includes six new chapters on a wide range of topics, including the clinical performance of highly crosslinked polyethylene (HXLPE) in hip and knee replacement, an overview of antioxidant stabilization for UHMWPE, and the medical applications of UHMWPE fibersState-of-the-art coverage of the latest UHMWPE technology, orthopedic applications, biomaterial characterization, and engineering aspects from recognized leaders in the field

Table of Contents

A Primer on Polyethylene Biomaterials 
Processing of UHMWPE. 
Processing of UHMWPE Fibers
Processing of HDPE Biomaterials
Sterilization and Packaging of Polyethylene Bioamaterials
The Origins of UHMWPE in Orthopedics 
Clinical Performance of Conventional UHMWPE in Hip Replacements 
Chapter 8. Clinical Performance of HLXPEs in Hip Replacement 
The Rise and Fall of Metal-on-Metal Hip Replacement: An Erstwhile Alternative Bearing 
Ceramic Biomaterials and UHMWPE in Hip Replacement 
Origins and Adaptations of UHMWPE for Knee Replacements 
Clinical Performance of Conventional UHMWPE in Knee Replacements 
Clinical Performance of Alternative Bearings in Knee Replacement 
Applications of UHMWPE in Shoulder Replacements 
Applications of UHMWPE in Elbow Replacements 
Applications of UHMWPE in Ankle Replacements 
Applications of UHMWPE in the Spine 
UHMWPE Articulations with PEEK 
Highly Crosslinked and Melt-Stabilized UHMWPE 
Highly Crosslinked and Annealed UHMWPE 
Mechanical Annealing of UHMWPE 
Overview of Antioxidant Stabilization for UHMWPE
UHMWPE Blended with Vitamin E
Highly Crosslinked UHMWPE Doped with Vitamin E 
UHMWPE Blended with a Novel Phenolic Antioxidant 
MPC Grafted UHMWPE
UHMWPE Structural Composites 
UHMWPE-Hyaluronan Polymer Networks
High-Pressure Crystallized UHMWPE 
Compendium of UHMWPE Biomaterials 
Mechanisms of Crosslinking, Oxidative Degradation, and Antioxidant Stabilization of UHMWPE 
In Vivo Degradation of UHMWPE 
. Biologic Reactions to UHMWPE Wear Particles
Characterization of UHMWPE
Tribological Assessment of UHMWPE in the Pin-on-Disc Simulators 
Tribological Assessment of UHMWPE in the Hip 
Tribological Assessment of UHMWPE in the Knee 
Characterization of UHMWPE Wear Particles 
Clinical Surveillance of UHMWPE Using Radiographic Methods 
Electron Spin Resonance and Macroradical Detection in UHMWPE
Fatigue and Fracture Behavior of UHMWPE 
Notch Sensitivity of UHMWPE 
Development and Application of the Small Punch Test to UHMWPE 
Micro- and Nanoindentation Testing of UHMWPE 
MicroCT Analysis of Wear and Damage in UHMWPE
Computer Modeling and Simulation of UHMWPE