Systems and Synthetic Metabolic Engineering

Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area.

Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biologyCovers introductory, regulatory, strategies, production and challenges in the fieldWritten technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders

1. Systems biology, synthetic biology and metabolic engineering 2. Synthetic regulatory elements for fine-tuning gene expression 3. Systems and synthetic biology-aided biosynthesis pathway design 4. Refactoring and optimization of metabolic network 5. Harnessing the hierarchy of transcriptional regulation: engineering of the gene expression network for efficient production of biofuels 6. Systems metabolic engineering strategies for cell factories construction 7. High throughput screening for improving cellular and enzymatic properties 8. In vitro metabolic engineering: current status and recent progress 9. Systems and synthetic metabolic engineering for production of biochemicals 10. Systems and synthetic metabolic engineering: Challenges and prospects