A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects

A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects presents up-to-date knowledge in the field and provides a comprehensive summary of this area of study, including an overview on IBS, starting from its pathogenesis, including genetic, microbial and physiological background, through symptom recognition, diagnosis and IBS treatment, both non-pharmacological and pharmacological.

Compiles the most recent and comprehensive findings in pharmacological targets Highlights the role of extrinsic and intrinsic factors involved in disease developmentWritten by leading researchers in the field of Irritable Bowel Syndrome to address research challenges in the fieldIncludes bonus information on symptom recognition and diagnosis

1. Introduction to irritable bowel syndrome: General overview and epidemiology 2. Pathogenesis of irritable bowel syndrome 3. Irritable bowel syndrome and the brain-gut connection 4. The control of the intestinal epithelium integrity in irritable bowel syndrome patients 5. Irritable bowel syndrome and gut microbiota 6. Gender-related differences and significance of gonadal hormones in irritable bowel syndrome 7. Genetic aspect (with SNPs) of irritable bowel syndrome 8. Clinical diagnosis of irritable bowel syndrome 9. Biomarkers of irritable bowel syndrome 10. Irritable bowel syndrome: Current therapies and future perspectives 11. Pain in irritable bowel syndrome 12. Non-pharmacological approach in irritable bowel syndrome therapy  13. Diet in irritable bowel syndrome 14. Correlation of irritable bowel syndrome with psychiatric disorders 15. Preclinical models of irritable bowel syndrome