Novel Therapeutic Advances in Glioblastoma

Novel Therapeutic Advances in Glioblastoma, Volume 151 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Blood-brain barrier and pathophysiology of brain tumors, Promising strategies of glioblastoma treatment: personalized genotoxic therapy and stem cell transplantation, Extracellular matrix and biocompatible materials in glioblastoma treatment, Expression of Twist associated to microcirculation patterns of human glioma correlated with progression and survival of the patient, Advanced Multimodal Imaging in Differentiating Glioma Recurrence from Post-radiotherapy Changes, Advanced Multimodal Imaging in Differentiating Glioma Recurrence from Post-radiotherapy Changes, and much more.

Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the International Review of Neurobiology seriesUpdated release includes the latest information on glioblastomas

1. Pathophysiology of blood-brain barrier in brain tumor. Novel therapeutic advances using nanomedicine

Hari Shanker Sharma, Dafin F. Muresanu, Rudy J. Castellani, Ala Nozari, José Vicente Lafuente, Z. Ryan Tian, Seaab Sahib, Igor Bryukhovetskiy, Andrey Bryukhovetskiy, Anca D. Buzoianu, Ranjana Patnaik, Lars Wiklund and Aruna Sharma

2. Personalized therapy and stem cell transplantation for pro-inflammatory modulation of cancer stem cells microenvironment in glioblastoma: Review

Igor Bryukhovetskiy, Oleg Pak, Yuri Khotimchenko, Andrey Bryukhovetskiy, Aruna Sharma and Hari Shanker Sharma

3. New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221

Zhiqiang Zhang, Yun Chen, Huijing Chen, Yanying Yang, Cong Li, Wengang Zhan, Qijia Tan, Caijun Xie, Hari Shanker Sharma and Aruna Sharma

4. Hydrogels based on modified pectins capable of modulating neural cell behavior as prospective biomaterials in glioblastoma treatment

Andrei Belousov, Sergei Titov, Nikita Shved, Grigorii Malykin, Valeri Kovalev, Irina Suprunova, Yuri Khotimchenko and Vadim Kumeiko

5. Fluorescein-guided surgery for spinal gliomas: Analysis of 220 consecutive cases

Zhenxing Sun, Linkai Jing, Yingwei Fan, Huifang Zhang, Lin Chen, Guihuai Wang, Hari Shanker Sharma and James Wang

6. Molecular determinants of the interaction between glioblastoma CD133⁺ cancer stem cells and the extracellular matrix

Valeriy Shevchenko, Natalia Arnotskaya, Oleg Pak, Aruna Sharma, Hari Shanker Sharma, Yuri Khotimchenko, Andrey Bryukhovetskiy and Igor Bryukhovetskiy

7. Surgical treatment of low-grade brain tumors associated with epilepsy

Wei Zhang, Junxi Chen, Gang Hua, Dan Zhu, Qinghua Tan, Liming Zhang, Genbo Wang, Meichao Ding, Xiangshu Hu, Hua Li , Hari Shanker Sharma and Qiang Guo

8. Proteins of Wnt signaling pathway in cancer stem cells of human glioblastoma

Valeriy Shevchenko, Natalia Arnotskaya, Sergei Zaitsev, Aruna Sharma, Hari Shanker Sharma, Andrey Bryukhovetskiy, Oleg Pak, , Yuri Khotimchenko and Igor Bryukhovetskiy

9. Expression of Twist associated to microcirculation patterns of human glioma correlated with progression and survival of the patient

Cong Li, Yinsheng Chen, Qingping Zhang, Chengcheng Guo, Furong Chen, Shaoyan Xi, Jing Zeng, Chao Ke, Hari Shanker Sharma and Zhongping Chen

10. Transforming growth factor-ß mimics the key proteome properties of CD133^- differentiated and CD133⁺ cancer stem cells in glioblastoma

Igor Bryukhovetskiy, Valeriy Shevchenko, Natalia Arnotskaya, Tatyana Kushnir, Oleg Pak, Zgoda Victor, Sergey Zaitsev, Yuri Khotimchenko, Andrey Bryukhovetskiy, Aruna Sharma and Hari Shanker Sharma

11. Inhibitory effect of Siwei Xiaoliuyin on glioma angiogenesis in nude mice

Zhiqiang Zhang, Wengang Zhan, Huijing Chen, Yun Chen, Cong Li, Yanying Yang, Qijia Tan, Caijun Xie, Hari Shanker Sharma and Aruna Sharma

12. Pro-inflammatory modification of cancer cells microsurroundings increases the survival rates for rats with low differentiated malignant glioma of brain

Sergei Zaitsev, Hari Shanker Sharma, Aruna Sharma, Igor Manzhulo, Alexander Polevshchikov, Igor Kudriavtsev, Yuri Khotimchenko, Oleg Pak, Andrey Bryukhovetskiy and Igor Bryukhovetskiy

13. Advanced multimodal imaging in differentiating glioma recurrence from post-radiotherapy changes

Cong Li, Yan-ling Gan, Huijing Chen, Yun Chen, Yuer Deng, Wengang Zhan, Qijia Tan, Caijun Xie, Hari Shanker Sharma and Zhiqiang Zhang

14. Alkaloids of fascaplysin are promising chemotherapeutic agents for the treatment of glioblastoma: Review

Irina Lyakhova, Mariia Piatkova, Valeriia Gulaia, Aleksandr Romanishin, Mikhail Shmelev, Andrey Bryukhovetskiy, Aruna Sharma, Hari Shanker Sharma, Rodion Khotimchenko and Igor Bryukhovetskiy

15. 3-Bromofascaplysin is a prospective chemical compound for developing new chemotherapy agents in glioblastoma treatment

Irina Lyakhova, Mariia Piatkova, Yuri Khotimchenko, Maxim Zhidkov,Alexey Kantemirov, Rodion Khotimchenko, Andrey Bryukhovetskiy, Aruna Sharma, Hari Shanker Sharma and Igor Bryukhovetskiy