Nanoformulation Strategies for Cancer Treatment

Nanoformulation Strategies for Cancer Treatment provides an up-to-date review on current developments and regulatory and clinical challenges in the field of nanopharmaceuticals and the effective treatment of diverse varieties of cancer. This important reference source is ideal for biomaterials scientists and pharmaceutical scientists working in the area of cancer diagnosis and therapy. Due to the high cost of traditional cancer treatment types, researchers have increasingly looked for new ways to augment the therapeutic performance of existing drug candidates. The use of nanotechnology-based approaches have gained significant momentum, thus leading to the launch of a series of new drug products.

As nanopharmaceuticals improve the therapeutic performance of cancer therapy drugs, but also provide opportunities for site-specific drug targeting in tumors, this work is a welcomed resource on the topics discussed.

Highlights the application of nanoformulations, including liposomes, nanoparticles and nanobiomaterials for targeted drug delivery to cancer cellsExplores recent advances made using novel nanoformulations containing herbal drugs and biotechnology based therapeutic strategies for cancer treatmentAssesses the regulatory hurdles that are necessary for the successful clinical translation of nanomedicines from the laboratory into the market

Section A: General consideration on cancer nanomedicines 1. Nanomedicine for combinational anticancer drug therapeutics: Recent advances, challenges and future perspectives 2. Market research in cancer therapeutics: New and Generic Product Development 3. Regulatory perspectives of nanomedicines for cancer treatment

Section B: Formulation technologies in cancer nanomedicines 4. Biopharmaceutical challenges in using lipid nanoparticles for oral chemotherapy 5. Polymeric nanoparticles for potential drug delivery applications in cancer 6. Lipid-polymer hybrid nanoparticles: Production, characterization and formulation of nucleic acids for cancer therapy 7. Metallic nanoparticles in drug delivery and cancer treatment 8. Liposomal nanotherapeutics in cancer treatment 9. Surface decoration strategies in nanomedicines for cancer treatment 10. Protein based nanomedicines as anticancer drug delivery platform 11. Phyto actives loaded nanocarriers for liver cancer treatment

Section C: Innovative treatment strategies in cancer nanomedicines 12. Nanotechnology assisted medical devices in cancer treatment 13. Immunotherapy as a boon in cancer treatment 14. Antibody-drug combination therapy in cancer treatment 15. Immune-chemo combination therapy in cancer treatment

Section D: Clinical perspectives in cancer nanomedicines 16. Formulation and biological stability of the nanomedicines in cancer treatment 17. Nanotoxicology profiling of cancer nanomedicines 18. Clinical translation status of nanoformulations

Section E: Regulatory perspectives in cancer nanomedicines 19. GLP and cGMP requirements in the development of cancer nanomedicines 20. Quality by Design approach for systematic development of nanopharmaceutical products