Cell Death Regulation in Health and Disease - Part A

Cell Death Regulation in Health and Disease - Part A, Volume 351, the latest release in the International Review of Cell and Molecular Biology reviews current advances in cell and molecular biology. The series publishes timely topics authored by prominent cell and molecular biologists. This release is part of a 3-part series which comprises a comprehensive view of cell death regulation in a variety of biological contexts. Chapters cover Membrane dynamics in cell death regulation, The role of necroptosis in intestinal dysfunction, Regulation of cell death in the cardiovascular system, Cell death in bacterial and viral infection, and much more.

Provides a comprehensive collection of front-of-the line research in the field of cell death regulationAuthored by established and active cell and molecular biologists and drawn from international sourcesIncludes invited review articles that cover selected topics in multiple organisms and disease settings

Preface: Life through death: Key role of cellular suicide for colonial and organismal homeostasis Johan Spetz and Lorenzo Galluzzi

1. Bcl-2 family proteins, beyond the veil Jason Andrew Glab, Zhipeng Cao and Hamsa Puthalakath

2. Mcl-1 as a “barrier” in cancer treatment: Can we target it now? Nikolai V. Pervushin, Viacheslav V. Senichkin, Boris Zhivotovsky and Gelina S. Kopeina

3. TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response Daniela Stöhr, Albert Jeltsch and Markus Rehm

4. Type 3 IP3 receptors: The chameleon in cancer Nicolas Rosa, Flore Sneyers, Jan B. Parys and Geert Bultynck

5. On the role of sphingolipids in cell survival and death Elisabetta Iessi, Matteo Marconi, Valeria Manganelli, Maurizio Sorice, Walter Malorni, Tina Garofalo and Paola Matarrese

6. A lipid perspective on regulated cell death Hector Flores-Romero, Uris Ros and Ana J. García Sáez