Tumor Vascularization

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.

Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vesselsProvides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differencesEncompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

1. Sprouting and non-sprouting angiogenesis in tumors 2. Nonangiogenic tumor growth 3. Vascular co-option 4. Pericyte mimicry: an embryonic-like mechanism for tumor metastasis 5. Vasculogenic mimicry 6. Postnatal vasculogenesis 7. The perivascular niche 8. Zebrafish as an experimental model to study tumor angiogenesis 9. Clinical implications