The Heparins: Basic and Clinical Aspects

The Heparins: Properties and Clinical Applications brings the latest information on heparin, one of the world's most widely used drugs. The book describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of various heparins are illustrated, with their function as anticoagulants delineated. This comprehensive resource arms researchers and clinicians with a concise and practical source that will assist in biomedical research, medical practice, and in improving patient outcomes.

Describes new pharmaceuticals derived from heparin that are devoid of anticoagulant activity, but still retain anti-inflammatory and anti-proliferative propertiesDiscusses the development of non-anticoagulant heparins for the treatment of diseases, including asthma and cancerPresents the history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders

Part I. Historical Development and Properties 1. Anticoagulant Heparins 2. Non-anticoagulant Heparins

Part II. Clinical Applications 3. Prevention of Thrombosis 4. Therapy for Thrombosis

Part III. Adverse Effects 5. Bleeding, heparin-induced thrombocytopenia