Recent Advances in Applications of Name Reactions in Multicomponent Reactions

Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs.

These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described.

Includes the synthesis of many heterocycles, which is ideal for synthetic organic chemists engaged in the synthesis of heterocyclic systemsCovers the recent advances of asymmetric synthesis of a wide range of heterocycles in satisfactory enantioselectivities (ees) or distereoselectivities (des)Reviews the synthesis of a wide variety of interesting heterocycles by using a combination of different and versatile name reactions via MCRs

1. Introduction

2. Applications of name reactions in Multicomponent reactions 2.1. Advances in Ugi reaction in MCRs 2.2. Advances in Passerini reaction in MCRS 2.3. Advances in Click reaction in MCRS 2.4. Advances in Knoevenagel reaction in MCRS 2.5. Advances in Michael reaction in MCRS 2.6. Advances in Aldol reaction in MCRS 2.7. Advances in Mannich reaction in MCRS 2.8. Advances in Diels-Alder reaction in MCRS 2.9. Advances in Heck reaction in MCRS 2.10. Advances in Huisgen reaction in MCRS 2.11. Advances in Suzuki reaction in MCRS

3. Multicomponent reaction via combinations of name reactions 3.1. Knoevenagel Reaction/Michael reaction 3.2. Knoevenagel Reaction/Diels-Alder reaction 3.3. Michael Addition/Aldol reaction 3.4. Michael Addition/Mannich reaction 3.5. Ugi reaction/Heck reaction 3.6. Ugi Reaction/Deils-Alder reaction 3.7. Ugi Reaction/Huisgen reaction 3.8. Ugi Reaction/Aldol reaction 3.9. Heck Reaction/Suzuki reaction Conclusion References